Observations on the ultrastructure of a rat mammary gland treated with harmal and borage
Background : It had been indentified by histological, histochemical and morphometrical studies that peganum harmala is a mammogenic herb and borage officinalis is a lactogenic one . To complete our investigation about these two herbs , we performed electron microscopical study. Materials and methods...
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| Format: | Article |
| Language: | English |
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College of Medicine University of Baghdad
2007-04-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1441 |
| _version_ | 1797332203672174592 |
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| author | Malak A. Al- Yawer Wasan Al- Saidi Shatha M. Al-Faisaly Salim R. Hamoudi |
| author_facet | Malak A. Al- Yawer Wasan Al- Saidi Shatha M. Al-Faisaly Salim R. Hamoudi |
| author_sort | Malak A. Al- Yawer |
| collection | DOAJ |
| description | Background : It had been indentified by histological, histochemical and morphometrical studies that peganum harmala is a mammogenic herb and borage officinalis is a lactogenic one . To complete our investigation about these two herbs , we performed electron microscopical study.
Materials and methods : Rats were grouped according to their physiological status into three groups . Each group was subdivided in to three subgroups : one control and two experimental . The two experimental group were treated daily; the 1st one with an aqueous extract of peganum harmala seeds and the 2nd with an aqueous extract of borage officinalis flowers . After two weeks of treatment , mammary glands were employed for electron microscopical study.
Results : In virgin rats , the epithelial and myoepithelial cells were partially differentiated when harmal was given and completely differentiated when borage was given . In pregnant rats , harmal and borage optimize mammary parenchymal growth and induce lactation when these herbs were given. In lactating rats ,these herbs exhibited a picture similar to control lactating group but the budding of lipid droplets and the swelling of secretary vesicles were markedly increased.
Conclusion: Both harmal and borage stimulate the release of prolactin and induce galactogenesis during pregnancy and promote it during lactation . |
| first_indexed | 2024-03-08T07:46:08Z |
| format | Article |
| id | doaj.art-ad4ff1b3bf0c4c5aa146e109bbdebd38 |
| institution | Directory Open Access Journal |
| issn | 0041-9419 2410-8057 |
| language | English |
| last_indexed | 2024-03-08T07:46:08Z |
| publishDate | 2007-04-01 |
| publisher | College of Medicine University of Baghdad |
| record_format | Article |
| series | مجلة كلية الطب |
| spelling | doaj.art-ad4ff1b3bf0c4c5aa146e109bbdebd382024-02-02T16:15:59ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572007-04-01491Observations on the ultrastructure of a rat mammary gland treated with harmal and borageMalak A. Al- Yawer0Wasan Al- Saidi1Shatha M. Al-Faisaly2Salim R. Hamoudi3University of Baghdad / College of MedicineUniversity of Al- Mustansiryah / College of ScienceAl-Nahrain University / College of MedicineUniversity of Baghdad / College of MedicineBackground : It had been indentified by histological, histochemical and morphometrical studies that peganum harmala is a mammogenic herb and borage officinalis is a lactogenic one . To complete our investigation about these two herbs , we performed electron microscopical study. Materials and methods : Rats were grouped according to their physiological status into three groups . Each group was subdivided in to three subgroups : one control and two experimental . The two experimental group were treated daily; the 1st one with an aqueous extract of peganum harmala seeds and the 2nd with an aqueous extract of borage officinalis flowers . After two weeks of treatment , mammary glands were employed for electron microscopical study. Results : In virgin rats , the epithelial and myoepithelial cells were partially differentiated when harmal was given and completely differentiated when borage was given . In pregnant rats , harmal and borage optimize mammary parenchymal growth and induce lactation when these herbs were given. In lactating rats ,these herbs exhibited a picture similar to control lactating group but the budding of lipid droplets and the swelling of secretary vesicles were markedly increased. Conclusion: Both harmal and borage stimulate the release of prolactin and induce galactogenesis during pregnancy and promote it during lactation .http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1441Mammary gland , Electron microscope , Harmal , Borage |
| spellingShingle | Malak A. Al- Yawer Wasan Al- Saidi Shatha M. Al-Faisaly Salim R. Hamoudi Observations on the ultrastructure of a rat mammary gland treated with harmal and borage مجلة كلية الطب Mammary gland , Electron microscope , Harmal , Borage |
| title | Observations on the ultrastructure of a rat mammary gland treated with harmal and borage |
| title_full | Observations on the ultrastructure of a rat mammary gland treated with harmal and borage |
| title_fullStr | Observations on the ultrastructure of a rat mammary gland treated with harmal and borage |
| title_full_unstemmed | Observations on the ultrastructure of a rat mammary gland treated with harmal and borage |
| title_short | Observations on the ultrastructure of a rat mammary gland treated with harmal and borage |
| title_sort | observations on the ultrastructure of a rat mammary gland treated with harmal and borage |
| topic | Mammary gland , Electron microscope , Harmal , Borage |
| url | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1441 |
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