Spontaneous regression of primitive Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare, aggressive skin tumor that mainly occurs in the elderly with a generally poor prognosis. Like all skin cancers, its incidence is rising. Despite the poor prognosis, a few reports of spontaneous regression have been published. We describe the case of a 89-year-o...
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Format: | Article |
Language: | English |
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SAGE Publishing
2015-12-01
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Series: | Rare Tumors |
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Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/5961 |
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author | Fernando Cirillo |
author_facet | Fernando Cirillo |
author_sort | Fernando Cirillo |
collection | DOAJ |
description | Merkel cell carcinoma (MCC) is a rare, aggressive skin tumor that mainly occurs in the elderly with a generally poor prognosis. Like all skin cancers, its incidence is rising. Despite the poor prognosis, a few reports of spontaneous regression have been published. We describe the case of a 89-year-old male patient who presented two MCC lesions of the scalp. Following biopsy the lesions underwent complete regression with no clinical evidence of residual tumor up to 24 months. The current knowledge of MCC and the other cases of spontaneous regression described in the literature are reviewed. |
first_indexed | 2024-12-11T01:30:01Z |
format | Article |
id | doaj.art-ad52fdad09bb4b5b896a26d44693cde1 |
institution | Directory Open Access Journal |
issn | 2036-3605 2036-3613 |
language | English |
last_indexed | 2024-12-11T01:30:01Z |
publishDate | 2015-12-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Rare Tumors |
spelling | doaj.art-ad52fdad09bb4b5b896a26d44693cde12022-12-22T01:25:23ZengSAGE PublishingRare Tumors2036-36052036-36132015-12-017410.4081/rt.2015.59613244Spontaneous regression of primitive Merkel cell carcinomaFernando Cirillo0Department of Surgery, General Surgery Unit, Rare Hormonal Tumors Group, AO Istituti Ospitalieri, CremonaMerkel cell carcinoma (MCC) is a rare, aggressive skin tumor that mainly occurs in the elderly with a generally poor prognosis. Like all skin cancers, its incidence is rising. Despite the poor prognosis, a few reports of spontaneous regression have been published. We describe the case of a 89-year-old male patient who presented two MCC lesions of the scalp. Following biopsy the lesions underwent complete regression with no clinical evidence of residual tumor up to 24 months. The current knowledge of MCC and the other cases of spontaneous regression described in the literature are reviewed.http://www.pagepress.org/journals/index.php/rt/article/view/5961Merkel cell carcinomaspontaneous regressionimmune response |
spellingShingle | Fernando Cirillo Spontaneous regression of primitive Merkel cell carcinoma Rare Tumors Merkel cell carcinoma spontaneous regression immune response |
title | Spontaneous regression of primitive Merkel cell carcinoma |
title_full | Spontaneous regression of primitive Merkel cell carcinoma |
title_fullStr | Spontaneous regression of primitive Merkel cell carcinoma |
title_full_unstemmed | Spontaneous regression of primitive Merkel cell carcinoma |
title_short | Spontaneous regression of primitive Merkel cell carcinoma |
title_sort | spontaneous regression of primitive merkel cell carcinoma |
topic | Merkel cell carcinoma spontaneous regression immune response |
url | http://www.pagepress.org/journals/index.php/rt/article/view/5961 |
work_keys_str_mv | AT fernandocirillo spontaneousregressionofprimitivemerkelcellcarcinoma |