Spontaneous regression of primitive Merkel cell carcinoma

Merkel cell carcinoma (MCC) is a rare, aggressive skin tumor that mainly occurs in the elderly with a generally poor prognosis. Like all skin cancers, its incidence is rising. Despite the poor prognosis, a few reports of spontaneous regression have been published. We describe the case of a 89-year-o...

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Main Author: Fernando Cirillo
Format: Article
Language:English
Published: SAGE Publishing 2015-12-01
Series:Rare Tumors
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/rt/article/view/5961
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author Fernando Cirillo
author_facet Fernando Cirillo
author_sort Fernando Cirillo
collection DOAJ
description Merkel cell carcinoma (MCC) is a rare, aggressive skin tumor that mainly occurs in the elderly with a generally poor prognosis. Like all skin cancers, its incidence is rising. Despite the poor prognosis, a few reports of spontaneous regression have been published. We describe the case of a 89-year-old male patient who presented two MCC lesions of the scalp. Following biopsy the lesions underwent complete regression with no clinical evidence of residual tumor up to 24 months. The current knowledge of MCC and the other cases of spontaneous regression described in the literature are reviewed.
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spelling doaj.art-ad52fdad09bb4b5b896a26d44693cde12022-12-22T01:25:23ZengSAGE PublishingRare Tumors2036-36052036-36132015-12-017410.4081/rt.2015.59613244Spontaneous regression of primitive Merkel cell carcinomaFernando Cirillo0Department of Surgery, General Surgery Unit, Rare Hormonal Tumors Group, AO Istituti Ospitalieri, CremonaMerkel cell carcinoma (MCC) is a rare, aggressive skin tumor that mainly occurs in the elderly with a generally poor prognosis. Like all skin cancers, its incidence is rising. Despite the poor prognosis, a few reports of spontaneous regression have been published. We describe the case of a 89-year-old male patient who presented two MCC lesions of the scalp. Following biopsy the lesions underwent complete regression with no clinical evidence of residual tumor up to 24 months. The current knowledge of MCC and the other cases of spontaneous regression described in the literature are reviewed.http://www.pagepress.org/journals/index.php/rt/article/view/5961Merkel cell carcinomaspontaneous regressionimmune response
spellingShingle Fernando Cirillo
Spontaneous regression of primitive Merkel cell carcinoma
Rare Tumors
Merkel cell carcinoma
spontaneous regression
immune response
title Spontaneous regression of primitive Merkel cell carcinoma
title_full Spontaneous regression of primitive Merkel cell carcinoma
title_fullStr Spontaneous regression of primitive Merkel cell carcinoma
title_full_unstemmed Spontaneous regression of primitive Merkel cell carcinoma
title_short Spontaneous regression of primitive Merkel cell carcinoma
title_sort spontaneous regression of primitive merkel cell carcinoma
topic Merkel cell carcinoma
spontaneous regression
immune response
url http://www.pagepress.org/journals/index.php/rt/article/view/5961
work_keys_str_mv AT fernandocirillo spontaneousregressionofprimitivemerkelcellcarcinoma