Intact Proviral DNA Analysis of the Brain Viral Reservoir and Relationship to Neuroinflammation in People with HIV on Suppressive Antiretroviral Therapy

HIV establishes a persistent viral reservoir in the brain despite viral suppression in blood to undetectable levels on antiretroviral therapy (ART). The brain viral reservoir in virally suppressed HIV+ individuals is not well-characterized. In this study, intact, defective, and total HIV proviral ge...

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Bibliographic Details
Main Authors: Dana Gabuzda, Jun Yin, Vikas Misra, Sukrutha Chettimada, Benjamin B. Gelman
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/4/1009