Intact Proviral DNA Analysis of the Brain Viral Reservoir and Relationship to Neuroinflammation in People with HIV on Suppressive Antiretroviral Therapy

Intact Proviral DNA Analysis of the Brain Viral Reservoir and Relationship to Neuroinflammation in People with HIV on Suppressive Antiretroviral Therapy

HIV establishes a persistent viral reservoir in the brain despite viral suppression in blood to undetectable levels on antiretroviral therapy (ART). The brain viral reservoir in virally suppressed HIV+ individuals is not well-characterized. In this study, intact, defective, and total HIV proviral ge...

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Bibliographic Details
Main Authors:	Dana Gabuzda, Jun Yin, Vikas Misra, Sukrutha Chettimada, Benjamin B. Gelman
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	Viruses
Subjects:	HIV reservoirs intact proviral DNA assay intact proviral genomes HIV-associated neurocognitive disorders neuroinflammation
Online Access:	https://www.mdpi.com/1999-4915/15/4/1009

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