Comparison and Evaluation of the Effects of Rib and Lung Inhomogeneities on Lung Dose in Breast Brachytherapy using a Treatment Planning System and the MCNPX Code
Introduction: This study investigates to what extent the computed dose received by lung tissue in a commercially available treatment planning system (TPS) for 192Ir high-dose-rate breast brachytherapy is accurate in view of tissue inhomogeneities and presence of ribs. Materials and Methods: A CT sca...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2010-09-01
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| Series: | Iranian Journal of Medical Physics |
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| Online Access: | http://ijmp.mums.ac.ir/article_7250_d033726042bbfec6c1812f2cdb332c1a.pdf |
| _version_ | 1818305095783153664 |
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| author | Hossein Salehi Yazdi Mojtaba Shamsaei Hamid Reza Shabani Ramin Jaberi Saeed Setayeshi |
| author_facet | Hossein Salehi Yazdi Mojtaba Shamsaei Hamid Reza Shabani Ramin Jaberi Saeed Setayeshi |
| author_sort | Hossein Salehi Yazdi |
| collection | DOAJ |
| description | Introduction: This study investigates to what extent the computed dose received by lung tissue in a commercially available treatment planning system (TPS) for 192Ir high-dose-rate breast brachytherapy is accurate in view of tissue inhomogeneities and presence of ribs. Materials and Methods: A CT scan of the breast was used to construct a patient-equivalent phantom in the clinical treatment planning system. An implant involving 13 plastic catheters and 383 programmed source dwell positions were simulated using the MCNPX code. Results: The results were compared with the corresponding commercial TPS in the form of isodoses and cumulative dose–volume histogram in breast, lung and ribs. The comparison of Monte Carlo results and TPS calculation showed that the isodoses greater than 62% in the breast that were located rather close to the implant or away from the breast curvature surface and lung boundary were in good agreement. TPS calculations, however, overestimated dose in the lung for lower isodose contours and points that were lying near the breast-air boundary and relatively away from the implant. Discussion and Conclusions: Taking into account the ribs and entering the actual data for breast, rib and lung, revealed an average overestimation of dose in lung in the TPS calculation. |
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| id | doaj.art-ad5480d7949c4229916b63eca24cf1b6 |
| institution | Directory Open Access Journal |
| issn | 2345-3672 2345-3672 |
| language | English |
| last_indexed | 2024-12-13T06:21:09Z |
| publishDate | 2010-09-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Medical Physics |
| spelling | doaj.art-ad5480d7949c4229916b63eca24cf1b62022-12-21T23:56:50ZengMashhad University of Medical SciencesIranian Journal of Medical Physics2345-36722345-36722010-09-0173212710.22038/ijmp.2010.72507250Comparison and Evaluation of the Effects of Rib and Lung Inhomogeneities on Lung Dose in Breast Brachytherapy using a Treatment Planning System and the MCNPX CodeHossein Salehi Yazdi0Mojtaba Shamsaei1Hamid Reza Shabani2Ramin Jaberi3Saeed Setayeshi4M.Sc. Student of Medical Radiation Engineering , Nuclear Engineering and Physics Dept., Amirkabir University of Technology, Tehran, IranAssistant Professor, Nuclear Engineering and Physics Dept., Amirkabir University of Technology, Tehran, IranM.Sc. Student of Medical Physics, Medical Physics Dept., Tehran University of Medical Sciences, Tehran, IranRadiotherapy Physicist, Cancer Institute, Imam Khomeini Hospital, Tehran, IranAssociate Professor, Nuclear Engineering and Physics Dept., Amirkabir University of Technology, Tehran, IranIntroduction: This study investigates to what extent the computed dose received by lung tissue in a commercially available treatment planning system (TPS) for 192Ir high-dose-rate breast brachytherapy is accurate in view of tissue inhomogeneities and presence of ribs. Materials and Methods: A CT scan of the breast was used to construct a patient-equivalent phantom in the clinical treatment planning system. An implant involving 13 plastic catheters and 383 programmed source dwell positions were simulated using the MCNPX code. Results: The results were compared with the corresponding commercial TPS in the form of isodoses and cumulative dose–volume histogram in breast, lung and ribs. The comparison of Monte Carlo results and TPS calculation showed that the isodoses greater than 62% in the breast that were located rather close to the implant or away from the breast curvature surface and lung boundary were in good agreement. TPS calculations, however, overestimated dose in the lung for lower isodose contours and points that were lying near the breast-air boundary and relatively away from the implant. Discussion and Conclusions: Taking into account the ribs and entering the actual data for breast, rib and lung, revealed an average overestimation of dose in lung in the TPS calculation.http://ijmp.mums.ac.ir/article_7250_d033726042bbfec6c1812f2cdb332c1a.pdfBreast cancerBrachytherapyHigh Dose RateInhomogeneityMCNPXTreatment Planning System |
| spellingShingle | Hossein Salehi Yazdi Mojtaba Shamsaei Hamid Reza Shabani Ramin Jaberi Saeed Setayeshi Comparison and Evaluation of the Effects of Rib and Lung Inhomogeneities on Lung Dose in Breast Brachytherapy using a Treatment Planning System and the MCNPX Code Iranian Journal of Medical Physics Breast cancer Brachytherapy High Dose Rate Inhomogeneity MCNPX Treatment Planning System |
| title | Comparison and Evaluation of the Effects of Rib and Lung Inhomogeneities on Lung Dose in Breast Brachytherapy using a Treatment Planning System and the MCNPX Code |
| title_full | Comparison and Evaluation of the Effects of Rib and Lung Inhomogeneities on Lung Dose in Breast Brachytherapy using a Treatment Planning System and the MCNPX Code |
| title_fullStr | Comparison and Evaluation of the Effects of Rib and Lung Inhomogeneities on Lung Dose in Breast Brachytherapy using a Treatment Planning System and the MCNPX Code |
| title_full_unstemmed | Comparison and Evaluation of the Effects of Rib and Lung Inhomogeneities on Lung Dose in Breast Brachytherapy using a Treatment Planning System and the MCNPX Code |
| title_short | Comparison and Evaluation of the Effects of Rib and Lung Inhomogeneities on Lung Dose in Breast Brachytherapy using a Treatment Planning System and the MCNPX Code |
| title_sort | comparison and evaluation of the effects of rib and lung inhomogeneities on lung dose in breast brachytherapy using a treatment planning system and the mcnpx code |
| topic | Breast cancer Brachytherapy High Dose Rate Inhomogeneity MCNPX Treatment Planning System |
| url | http://ijmp.mums.ac.ir/article_7250_d033726042bbfec6c1812f2cdb332c1a.pdf |
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