Retroperitoneal schwannoma during pregnancy: A case report and practice-based overview
The retroperitoneum is the rarest site for Schwannomas, tumors that originate from Schwann cells and usually present as benign, slowly growing masses. During pregnancy, the routine application of ultrasound for fetal assessment has led to an increased rate of detection of maternal asymptomatic masse...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Case Reports in Women's Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214911224000110 |
| _version_ | 1797287651606265856 |
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| author | Stefano Fruci Anna Fagotti Silvia Salvi Pierpaolo Mattogno Quintino Giorgio D'Alessandris Federica Totaro Aprile Antonia Carla Testa Antonio Lanzone Liverana Lauretti |
| author_facet | Stefano Fruci Anna Fagotti Silvia Salvi Pierpaolo Mattogno Quintino Giorgio D'Alessandris Federica Totaro Aprile Antonia Carla Testa Antonio Lanzone Liverana Lauretti |
| author_sort | Stefano Fruci |
| collection | DOAJ |
| description | The retroperitoneum is the rarest site for Schwannomas, tumors that originate from Schwann cells and usually present as benign, slowly growing masses. During pregnancy, the routine application of ultrasound for fetal assessment has led to an increased rate of detection of maternal asymptomatic masses, notably including the retroperitoneal ones. While most of these masses prove to be benign, it is imperative to consider the potential for malignancy. This report presents a rare case involving a woman diagnosed with bilateral adnexal cysts and a pre-sacral retroperitoneal mass during the first trimester of pregnancy. Surgical intervention was employed to remove ovarian tumors, and a biopsy was performed on the non-adnexal tumor to determine its nature. The histological examination revealed a bilateral borderline seromucinous tumor in the ovaries and identified a Schwannoma in the sacral mass. Despite the considerable size of the pre-sacral mass, which significantly impacted the patient's quality of life, successful measures were taken to achieve a near-term pregnancy, culminating in the delivery of a healthy baby. Subsequently the patient underwent neurosurgical treatment of the substantial pre-sacral Schwannoma. The discovery of a Schwannoma during pregnancy can evoke concerns among healthcare practitioners, touching upon potential malignancy risks, accelerated tumor growth, and impacts on fetal well-being. This paper provides a comprehensive, practice-based overview of these critical aspects. |
| first_indexed | 2024-03-07T18:36:27Z |
| format | Article |
| id | doaj.art-ad55197f47e84c7ab6c3b93f641a979b |
| institution | Directory Open Access Journal |
| issn | 2214-9112 |
| language | English |
| last_indexed | 2024-03-07T18:36:27Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Case Reports in Women's Health |
| spelling | doaj.art-ad55197f47e84c7ab6c3b93f641a979b2024-03-02T04:54:08ZengElsevierCase Reports in Women's Health2214-91122024-03-0141e00590Retroperitoneal schwannoma during pregnancy: A case report and practice-based overviewStefano Fruci0Anna Fagotti1Silvia Salvi2Pierpaolo Mattogno3Quintino Giorgio D'Alessandris4Federica Totaro Aprile5Antonia Carla Testa6Antonio Lanzone7Liverana Lauretti8UOC di Ostetricia e Patologia Ostetrica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, L.go Agostino Gemelli 8, Rome 00168, ItalyDipartimento Universitario di Scienze della Vita e Sanità pubblica - Sezione di Ginecologia ed Ostetricia - Università Cattolica del Sacro Cuore, L.go Francesco Vito 1, Rome 00168, Italy; UOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go Agostino Gemelli 8, Rome 00168, ItalyUOC di Ostetricia e Patologia Ostetrica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, L.go Agostino Gemelli 8, Rome 00168, Italy; Dipartimento Universitario di Scienze della Vita e Sanità pubblica - Sezione di Ginecologia ed Ostetricia - Università Cattolica del Sacro Cuore, L.go Francesco Vito 1, Rome 00168, Italy; Corresponding author at: UOC di Patologia Ostetrica, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy.Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go Agostino Gemelli 8, Rome 00168, ItalyDepartment of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go Agostino Gemelli 8, Rome 00168, ItalyUOC di Ostetricia e Patologia Ostetrica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, L.go Agostino Gemelli 8, Rome 00168, ItalyDipartimento Universitario di Scienze della Vita e Sanità pubblica - Sezione di Ginecologia ed Ostetricia - Università Cattolica del Sacro Cuore, L.go Francesco Vito 1, Rome 00168, Italy; UOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go Agostino Gemelli 8, Rome 00168, ItalyUOC di Ostetricia e Patologia Ostetrica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, L.go Agostino Gemelli 8, Rome 00168, Italy; Dipartimento Universitario di Scienze della Vita e Sanità pubblica - Sezione di Ginecologia ed Ostetricia - Università Cattolica del Sacro Cuore, L.go Francesco Vito 1, Rome 00168, ItalyDepartment of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go Agostino Gemelli 8, Rome 00168, Italy; Dipartimento Universitario di Neuroscienze - Università Cattolica del Sacro Cuore, L.go Francesco Vito 1, Rome 00168, ItalyThe retroperitoneum is the rarest site for Schwannomas, tumors that originate from Schwann cells and usually present as benign, slowly growing masses. During pregnancy, the routine application of ultrasound for fetal assessment has led to an increased rate of detection of maternal asymptomatic masses, notably including the retroperitoneal ones. While most of these masses prove to be benign, it is imperative to consider the potential for malignancy. This report presents a rare case involving a woman diagnosed with bilateral adnexal cysts and a pre-sacral retroperitoneal mass during the first trimester of pregnancy. Surgical intervention was employed to remove ovarian tumors, and a biopsy was performed on the non-adnexal tumor to determine its nature. The histological examination revealed a bilateral borderline seromucinous tumor in the ovaries and identified a Schwannoma in the sacral mass. Despite the considerable size of the pre-sacral mass, which significantly impacted the patient's quality of life, successful measures were taken to achieve a near-term pregnancy, culminating in the delivery of a healthy baby. Subsequently the patient underwent neurosurgical treatment of the substantial pre-sacral Schwannoma. The discovery of a Schwannoma during pregnancy can evoke concerns among healthcare practitioners, touching upon potential malignancy risks, accelerated tumor growth, and impacts on fetal well-being. This paper provides a comprehensive, practice-based overview of these critical aspects.http://www.sciencedirect.com/science/article/pii/S2214911224000110SchwannomaPregnancyUltrasoundMagnetic resonance imaging |
| spellingShingle | Stefano Fruci Anna Fagotti Silvia Salvi Pierpaolo Mattogno Quintino Giorgio D'Alessandris Federica Totaro Aprile Antonia Carla Testa Antonio Lanzone Liverana Lauretti Retroperitoneal schwannoma during pregnancy: A case report and practice-based overview Case Reports in Women's Health Schwannoma Pregnancy Ultrasound Magnetic resonance imaging |
| title | Retroperitoneal schwannoma during pregnancy: A case report and practice-based overview |
| title_full | Retroperitoneal schwannoma during pregnancy: A case report and practice-based overview |
| title_fullStr | Retroperitoneal schwannoma during pregnancy: A case report and practice-based overview |
| title_full_unstemmed | Retroperitoneal schwannoma during pregnancy: A case report and practice-based overview |
| title_short | Retroperitoneal schwannoma during pregnancy: A case report and practice-based overview |
| title_sort | retroperitoneal schwannoma during pregnancy a case report and practice based overview |
| topic | Schwannoma Pregnancy Ultrasound Magnetic resonance imaging |
| url | http://www.sciencedirect.com/science/article/pii/S2214911224000110 |
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