Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum Trial
Abstract Background Maintaining employment for adults with cancer is important, however, little is known about the impact of surgery for rectal cancer on an individual's capacity to return to work (RTW). This study aimed to determine the impact of laparoscopic vs. open resection on RTW at 12 mo...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.3623 |
| _version_ | 1818560240855023616 |
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| author | Chi Kin Law Kate Brewer Chris Brown Kate Wilson Lisa Bailey Wendy Hague John R. Simes Andrew Stevenson Michael Solomon Rachael L. Morton the Australasian Gastro‐Intestinal Trials Group (AGITG) ALaCaRT investigators |
| author_facet | Chi Kin Law Kate Brewer Chris Brown Kate Wilson Lisa Bailey Wendy Hague John R. Simes Andrew Stevenson Michael Solomon Rachael L. Morton the Australasian Gastro‐Intestinal Trials Group (AGITG) ALaCaRT investigators |
| author_sort | Chi Kin Law |
| collection | DOAJ |
| description | Abstract Background Maintaining employment for adults with cancer is important, however, little is known about the impact of surgery for rectal cancer on an individual's capacity to return to work (RTW). This study aimed to determine the impact of laparoscopic vs. open resection on RTW at 12 months. Methods Analyses were undertaken among participants randomized in the Australian Laparoscopic Cancer of the Rectum Trial (ALaCaRT), with work status available at baseline (presurgery), and 12 months. Multivariable logistic regression, adjusted for sociodemographic and clinical characteristics estimated the effect of surgery on RTW in any capacity, or return to preoperative work status at 12 months. Results About 228 of 449 (51%) surviving trial participants at 12 months completed work status questionnaires; mean age was 62 years, 66% males, 117 of these received laparoscopic resection (51%). Of 228, 120 were employed at baseline (90 full‐time, 30 part‐time). Overall RTW in 120 participants in paid work at baseline was 78% (84% laparoscopic, 70% open surgery). Those employed full‐time were more likely to RTW at 12 months (OR, 3.55; 95% CI, 1.02–12.31). Those with distant metastases at baseline were less likely to RTW (OR, 0.07; 95% CI, <0.01–0.83). Laparoscopic surgery was associated with a higher rate of RTW but did not reach statistical significance (OR 2.88; 95% CI, 0.95–8.76). Conclusions Full‐time work presurgery and the presence of metastatic disease predicts RTW status at 12 months. A laparoscopic‐assisted surgical approach to rectal cancer may facilitate more patients to RTW, however, larger sample sizes are likely needed to confirm this result. |
| first_indexed | 2024-12-14T00:35:57Z |
| format | Article |
| id | doaj.art-ad58900fb28044ec98f42d2c847fcbad |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-12-14T00:35:57Z |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-ad58900fb28044ec98f42d2c847fcbad2022-12-21T23:24:39ZengWileyCancer Medicine2045-76342021-01-0110255256210.1002/cam4.3623Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum TrialChi Kin Law0Kate Brewer1Chris Brown2Kate Wilson3Lisa Bailey4Wendy Hague5John R. Simes6Andrew Stevenson7Michael Solomon8Rachael L. Morton9the Australasian Gastro‐Intestinal Trials Group (AGITG) ALaCaRT investigatorsNHMRC Clinical Trials Centre The University of Sydney Camperdown NSW AustraliaNHMRC Clinical Trials Centre The University of Sydney Camperdown NSW AustraliaNHMRC Clinical Trials Centre The University of Sydney Camperdown NSW AustraliaNHMRC Clinical Trials Centre The University of Sydney Camperdown NSW AustraliaNHMRC Clinical Trials Centre The University of Sydney Camperdown NSW AustraliaNHMRC Clinical Trials Centre The University of Sydney Camperdown NSW AustraliaNHMRC Clinical Trials Centre The University of Sydney Camperdown NSW AustraliaFaculty of Medicine and Biomedical Sciences University of Queensland Herston Qld AustraliaInstitute of Academic Surgery Royal Prince Alfred Hospital University of Sydney Sydney NSW AustraliaNHMRC Clinical Trials Centre The University of Sydney Camperdown NSW AustraliaAbstract Background Maintaining employment for adults with cancer is important, however, little is known about the impact of surgery for rectal cancer on an individual's capacity to return to work (RTW). This study aimed to determine the impact of laparoscopic vs. open resection on RTW at 12 months. Methods Analyses were undertaken among participants randomized in the Australian Laparoscopic Cancer of the Rectum Trial (ALaCaRT), with work status available at baseline (presurgery), and 12 months. Multivariable logistic regression, adjusted for sociodemographic and clinical characteristics estimated the effect of surgery on RTW in any capacity, or return to preoperative work status at 12 months. Results About 228 of 449 (51%) surviving trial participants at 12 months completed work status questionnaires; mean age was 62 years, 66% males, 117 of these received laparoscopic resection (51%). Of 228, 120 were employed at baseline (90 full‐time, 30 part‐time). Overall RTW in 120 participants in paid work at baseline was 78% (84% laparoscopic, 70% open surgery). Those employed full‐time were more likely to RTW at 12 months (OR, 3.55; 95% CI, 1.02–12.31). Those with distant metastases at baseline were less likely to RTW (OR, 0.07; 95% CI, <0.01–0.83). Laparoscopic surgery was associated with a higher rate of RTW but did not reach statistical significance (OR 2.88; 95% CI, 0.95–8.76). Conclusions Full‐time work presurgery and the presence of metastatic disease predicts RTW status at 12 months. A laparoscopic‐assisted surgical approach to rectal cancer may facilitate more patients to RTW, however, larger sample sizes are likely needed to confirm this result.https://doi.org/10.1002/cam4.3623clinical trialincomelaparoscopyopen abdomen techniquesrectal neoplasmsreturn to work |
| spellingShingle | Chi Kin Law Kate Brewer Chris Brown Kate Wilson Lisa Bailey Wendy Hague John R. Simes Andrew Stevenson Michael Solomon Rachael L. Morton the Australasian Gastro‐Intestinal Trials Group (AGITG) ALaCaRT investigators Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum Trial Cancer Medicine clinical trial income laparoscopy open abdomen techniques rectal neoplasms return to work |
| title | Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum Trial |
| title_full | Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum Trial |
| title_fullStr | Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum Trial |
| title_full_unstemmed | Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum Trial |
| title_short | Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum Trial |
| title_sort | return to work following laparoscopic assisted resection or open resection for rectal cancer findings from alacart australasian laparoscopic cancer of the rectum trial |
| topic | clinical trial income laparoscopy open abdomen techniques rectal neoplasms return to work |
| url | https://doi.org/10.1002/cam4.3623 |
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