Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial
Introduction: Dentinal hypersensitivity is a prevalent and distressing dental condition characterised by acute, transient pain or discomfort arising from exposed dentin in response to external stimuli, such as variations in temperature, mechanical stimuli, or consumption of acidic or sweet foods...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2023-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/18532/64972_CE[Ra1]_F[SK]_QC(SHK_IS)_PF1(AP_SS)_PFA(KM)_PB(AP_OM)_PN(KM).pdf |
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| author | Ramesh Nagarajappa Priyanca Panigrahi Dharmashree Satyarup Jagruti Nanda Radha Prasanna Dalai Sourav Chandra Bidysagar Bal Sashikant Sethi |
| author_facet | Ramesh Nagarajappa Priyanca Panigrahi Dharmashree Satyarup Jagruti Nanda Radha Prasanna Dalai Sourav Chandra Bidysagar Bal Sashikant Sethi |
| author_sort | Ramesh Nagarajappa |
| collection | DOAJ |
| description | Introduction: Dentinal hypersensitivity is a prevalent and
distressing dental condition characterised by acute, transient
pain or discomfort arising from exposed dentin in response to
external stimuli, such as variations in temperature, mechanical
stimuli, or consumption of acidic or sweet foods. Dentinal
Hypersensitivity (DH) impacts daily activities, such as eating,
drinking, and oral hygiene practices. Dentifrices are commonly
used in the treatment of hypersensitivity, as they relieve
sensitivity by obstructing nerve pathways through the formation
of compounds.
Aim: The aim of the study is to evaluate and compare the
efficacy of two types of desensitising toothpastes, Vantej and
Dente 91, in treating DH.
Materials and Methods: A randomised controlled clinical trial
was conducted with 40 patients who had a minimum of two
hypersensitive teeth. The clinical investigation took place in
a dental set-up in Bhubaneswar, Odisha, from July to August
2022. The patients were randomly allocated to two groups
(20 in each group) in a 1:1 ratio for the Vantej and Dente 91
groups. Over a four-week period, the patients were instructed
to use the prescribed toothpaste twice daily. DH assessment
techniques included a Verbal Response Scale (VRS), air blast
stimulation, and cold stimulation, both at baseline and after the
four-week duration. Statistical analyses were performed using
the Mann-Whitney U test and Wilcoxon signed-rank test, with
the significance level set at p<0.05.
Results: The fourth-week scores compared to baseline scores
for the verbal scale, air blast stimulus, and cold sensitivity
methods in both groups showed a reduction in DH. In the
inter group comparison, the Dente 91 group exhibited greater
effectiveness compared to the Vantej group, with a significant
reduction in VRS (p=0.02) and air blast stimulus (p=0.01), but
not in cold sensitivity (p=0.09).
Conclusion: Both Vantej and Dente 91 toothpastes significantly
reduced dentinal hypersensitivity. However, the percentage
reduction was higher in the latter group, suggesting more
effective management of DH. Dente 91 could be considered
a promising alternative to the existing over-the-counter
desensitising toothpastes. |
| first_indexed | 2024-03-11T16:38:24Z |
| format | Article |
| id | doaj.art-ad58b82a08554f229527370fe3359be5 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-11T16:38:24Z |
| publishDate | 2023-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-ad58b82a08554f229527370fe3359be52023-10-23T09:55:52ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-10-011710010410.7860/JCDR/2023/64972.18532Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical TrialRamesh Nagarajappa0Priyanca Panigrahi1Dharmashree Satyarup2Jagruti Nanda3Radha Prasanna Dalai4Sourav Chandra Bidysagar Bal5Sashikant Sethi6Professor and Head, Department of Public Health Dentistry, The Oxford Dental College and Hospital, Banglore, Karanataka, India.Post Graduate Trainee, Department of Public Health Dentistry, Institute of Dental Sciences, Bhubaneswar, Odisha, India.Professor and Head, Department of Public Health Dentistry, Institute of Dental Sciences, Bhubaneswar, Odisha, India.Post Graduate Trainee, Department of Public Health Dentistry, Institute of Dental Sciences, Bhubaneswar, Odisha, India.Assistant Professor, Department of Public Health Dentistry, Institute of Dental Sciences, Bhubaneswar, Odisha, India.Assistant Professor, Department of Public Health Dentistry, Institute of Dental Sciences, Bhubaneswar, Odisha, India.Tutor, Department of Public Health Dentistry, Institute of Dental Sciences, Bhubaneswar, Odisha, India.Introduction: Dentinal hypersensitivity is a prevalent and distressing dental condition characterised by acute, transient pain or discomfort arising from exposed dentin in response to external stimuli, such as variations in temperature, mechanical stimuli, or consumption of acidic or sweet foods. Dentinal Hypersensitivity (DH) impacts daily activities, such as eating, drinking, and oral hygiene practices. Dentifrices are commonly used in the treatment of hypersensitivity, as they relieve sensitivity by obstructing nerve pathways through the formation of compounds. Aim: The aim of the study is to evaluate and compare the efficacy of two types of desensitising toothpastes, Vantej and Dente 91, in treating DH. Materials and Methods: A randomised controlled clinical trial was conducted with 40 patients who had a minimum of two hypersensitive teeth. The clinical investigation took place in a dental set-up in Bhubaneswar, Odisha, from July to August 2022. The patients were randomly allocated to two groups (20 in each group) in a 1:1 ratio for the Vantej and Dente 91 groups. Over a four-week period, the patients were instructed to use the prescribed toothpaste twice daily. DH assessment techniques included a Verbal Response Scale (VRS), air blast stimulation, and cold stimulation, both at baseline and after the four-week duration. Statistical analyses were performed using the Mann-Whitney U test and Wilcoxon signed-rank test, with the significance level set at p<0.05. Results: The fourth-week scores compared to baseline scores for the verbal scale, air blast stimulus, and cold sensitivity methods in both groups showed a reduction in DH. In the inter group comparison, the Dente 91 group exhibited greater effectiveness compared to the Vantej group, with a significant reduction in VRS (p=0.02) and air blast stimulus (p=0.01), but not in cold sensitivity (p=0.09). Conclusion: Both Vantej and Dente 91 toothpastes significantly reduced dentinal hypersensitivity. However, the percentage reduction was higher in the latter group, suggesting more effective management of DH. Dente 91 could be considered a promising alternative to the existing over-the-counter desensitising toothpastes.https://www.jcdr.net/articles/PDF/18532/64972_CE[Ra1]_F[SK]_QC(SHK_IS)_PF1(AP_SS)_PFA(KM)_PB(AP_OM)_PN(KM).pdfdentin desensitising agentslactoferrintoothpastes |
| spellingShingle | Ramesh Nagarajappa Priyanca Panigrahi Dharmashree Satyarup Jagruti Nanda Radha Prasanna Dalai Sourav Chandra Bidysagar Bal Sashikant Sethi Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial Journal of Clinical and Diagnostic Research dentin desensitising agents lactoferrin toothpastes |
| title | Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial |
| title_full | Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial |
| title_fullStr | Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial |
| title_full_unstemmed | Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial |
| title_short | Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial |
| title_sort | comparison of vantej and dente 91 toothpastes in the management of dentin hypersensitivity a randomised clinical trial |
| topic | dentin desensitising agents lactoferrin toothpastes |
| url | https://www.jcdr.net/articles/PDF/18532/64972_CE[Ra1]_F[SK]_QC(SHK_IS)_PF1(AP_SS)_PFA(KM)_PB(AP_OM)_PN(KM).pdf |
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