Geriatric cardiology in dogs - part 2: challenge with hf therapy in geriatric dogs: adverse drug reactions and comorbidities
In geriatric dogs, aging-specific changes in cardiovascular physiology, drug metabolism, drug pharmacokinetics and drug tolerance contribute to adverse drug reactions (ADRs). Comorbidities can also cause polypharmacy and thus drug-drug interactions. Adverse drug reactions for ACE inhibitors, β–block...
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| Format: | Article |
| Language: | English |
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Kafkas University, Faculty of Veterinary Medicine
2017-10-01
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| Series: | Kafkas Universitesi Veteriner Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://vetdergikafkas.org/pdf.php?id=2214 |
| _version_ | 1797800662121054208 |
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| author | Kürşad TURGUT Havva SÜLEYMANOĞLU Merve ERTAN Mehmet Ege İNCE |
| author_facet | Kürşad TURGUT Havva SÜLEYMANOĞLU Merve ERTAN Mehmet Ege İNCE |
| author_sort | Kürşad TURGUT |
| collection | DOAJ |
| description | In geriatric dogs, aging-specific changes in cardiovascular physiology, drug metabolism, drug pharmacokinetics and drug tolerance contribute
to adverse drug reactions (ADRs). Comorbidities can also cause polypharmacy and thus drug-drug interactions. Adverse drug reactions for
ACE inhibitors, β–blockers, furosemide, aldosterone antagonists and digoxin are common. Geriatric cardiology epitomizes the principle that
cardiovascular disease is only 1 component of a larger, multidimensional disease state with concomitant geriatric syndromes. Comorbidities
(cardiorenal syndrome, hypertension, diabetes mellitus, atherosclerotic disease, metabolic syndrome, obesity, chronic obstructive pulmonary
disease and frailty and cognitive dysfunction) are common, aggravate HF, complicate therapy and increase the total heart failure burden. |
| first_indexed | 2024-03-13T04:37:35Z |
| format | Article |
| id | doaj.art-ad58e8dc0baf4c2ca3df3ec8063af7e4 |
| institution | Directory Open Access Journal |
| issn | 1309-2251 |
| language | English |
| last_indexed | 2024-03-13T04:37:35Z |
| publishDate | 2017-10-01 |
| publisher | Kafkas University, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Kafkas Universitesi Veteriner Fakültesi Dergisi |
| spelling | doaj.art-ad58e8dc0baf4c2ca3df3ec8063af7e42023-06-19T06:44:10ZengKafkas University, Faculty of Veterinary MedicineKafkas Universitesi Veteriner Fakültesi Dergisi1309-22512017-10-0124231932610.9775/kvfd.2017.185812214Geriatric cardiology in dogs - part 2: challenge with hf therapy in geriatric dogs: adverse drug reactions and comorbiditiesKürşad TURGUT0Havva SÜLEYMANOĞLU1Merve ERTAN2Mehmet Ege İNCE3Department of Internal Medicine, Faculty of Veterinary Medicine, Near East University, Near East Boulevard, 99138, Nicosia - NORTHERN CYPRUSDepartment of Internal Medicine, Faculty of Veterinary Medicine, Near East University, Near East Boulevard, 99138, Nicosia - NORTHERN CYPRUSDepartment of Internal Medicine, Faculty of Veterinary Medicine, Near East University, Near East Boulevard, 99138, Nicosia - NORTHERN CYPRUSDepartment of Internal Medicine, Faculty of Veterinary Medicine, Near East University, Near East Boulevard, 99138, Nicosia - NORTHERN CYPRUSIn geriatric dogs, aging-specific changes in cardiovascular physiology, drug metabolism, drug pharmacokinetics and drug tolerance contribute to adverse drug reactions (ADRs). Comorbidities can also cause polypharmacy and thus drug-drug interactions. Adverse drug reactions for ACE inhibitors, β–blockers, furosemide, aldosterone antagonists and digoxin are common. Geriatric cardiology epitomizes the principle that cardiovascular disease is only 1 component of a larger, multidimensional disease state with concomitant geriatric syndromes. Comorbidities (cardiorenal syndrome, hypertension, diabetes mellitus, atherosclerotic disease, metabolic syndrome, obesity, chronic obstructive pulmonary disease and frailty and cognitive dysfunction) are common, aggravate HF, complicate therapy and increase the total heart failure burden.https://vetdergikafkas.org/pdf.php?id=2214geriatric cardiologyadverse drug reactionscomorbiditiesdog |
| spellingShingle | Kürşad TURGUT Havva SÜLEYMANOĞLU Merve ERTAN Mehmet Ege İNCE Geriatric cardiology in dogs - part 2: challenge with hf therapy in geriatric dogs: adverse drug reactions and comorbidities Kafkas Universitesi Veteriner Fakültesi Dergisi geriatric cardiology adverse drug reactions comorbidities dog |
| title | Geriatric cardiology in dogs - part 2: challenge with hf therapy in geriatric dogs: adverse drug reactions and comorbidities |
| title_full | Geriatric cardiology in dogs - part 2: challenge with hf therapy in geriatric dogs: adverse drug reactions and comorbidities |
| title_fullStr | Geriatric cardiology in dogs - part 2: challenge with hf therapy in geriatric dogs: adverse drug reactions and comorbidities |
| title_full_unstemmed | Geriatric cardiology in dogs - part 2: challenge with hf therapy in geriatric dogs: adverse drug reactions and comorbidities |
| title_short | Geriatric cardiology in dogs - part 2: challenge with hf therapy in geriatric dogs: adverse drug reactions and comorbidities |
| title_sort | geriatric cardiology in dogs part 2 challenge with hf therapy in geriatric dogs adverse drug reactions and comorbidities |
| topic | geriatric cardiology adverse drug reactions comorbidities dog |
| url | https://vetdergikafkas.org/pdf.php?id=2214 |
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