Integrated Love Wave Device Dedicated to Biomolecular Interactions Measurements in Aqueous Media
Mass-sensitive electro-acoustic devices such as surface acoustic wave (SAW)micro-balances, capable to operate with aqueous media are particularly favorable for thedevelopment of biosensors. Their dimensions and physical properties offer a large potentialin biological fluid investigations, especially...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2007-09-01
|
| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/7/9/1992/ |
| _version_ | 1818473759382700032 |
|---|---|
| author | Sylvain Ballandras Gilles Martin William Daniau Gwladys Lengaigne Bruno Cavallier Wilfrid Boireau Virginie Blondeau-Patissier |
| author_facet | Sylvain Ballandras Gilles Martin William Daniau Gwladys Lengaigne Bruno Cavallier Wilfrid Boireau Virginie Blondeau-Patissier |
| author_sort | Sylvain Ballandras |
| collection | DOAJ |
| description | Mass-sensitive electro-acoustic devices such as surface acoustic wave (SAW)micro-balances, capable to operate with aqueous media are particularly favorable for thedevelopment of biosensors. Their dimensions and physical properties offer a large potentialin biological fluid investigations, especially for measuring physical phenomenon (massdeposition, adsorption, pressure...). In this work, we propose a specific gratingconfiguration to lower the influence of viscosity of fluids which reduces the signal dynamicsof the surface wave transducers. A dedicated liquid cell also has been developed to isolatethe electro-active part of the device. The fabrication of the cell is achieved using theSU-8TMphoto-resist, allowing for manufacturing thick structures preventing any contact between thetested liquids and the transducers. Furthermore, the sensing area has been optimized tooptimize the sensor gravimetric sensitivity. The operation of the sensor is illustrated bydetecting bovine serum albumin (BSA) adsorption in the sensing area. |
| first_indexed | 2024-04-14T04:27:38Z |
| format | Article |
| id | doaj.art-ad5e204bc1db47f98eeffe1a45753a03 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-14T04:27:38Z |
| publishDate | 2007-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-ad5e204bc1db47f98eeffe1a45753a032022-12-22T02:12:15ZengMDPI AGSensors1424-82202007-09-01791992200310.3390/s7091992Integrated Love Wave Device Dedicated to Biomolecular Interactions Measurements in Aqueous MediaSylvain BallandrasGilles MartinWilliam DaniauGwladys LengaigneBruno CavallierWilfrid BoireauVirginie Blondeau-PatissierMass-sensitive electro-acoustic devices such as surface acoustic wave (SAW)micro-balances, capable to operate with aqueous media are particularly favorable for thedevelopment of biosensors. Their dimensions and physical properties offer a large potentialin biological fluid investigations, especially for measuring physical phenomenon (massdeposition, adsorption, pressure...). In this work, we propose a specific gratingconfiguration to lower the influence of viscosity of fluids which reduces the signal dynamicsof the surface wave transducers. A dedicated liquid cell also has been developed to isolatethe electro-active part of the device. The fabrication of the cell is achieved using theSU-8TMphoto-resist, allowing for manufacturing thick structures preventing any contact between thetested liquids and the transducers. Furthermore, the sensing area has been optimized tooptimize the sensor gravimetric sensitivity. The operation of the sensor is illustrated bydetecting bovine serum albumin (BSA) adsorption in the sensing area.http://www.mdpi.com/1424-8220/7/9/1992/Love wavesSAW resonatorsBiosensorBSA adsorption detection |
| spellingShingle | Sylvain Ballandras Gilles Martin William Daniau Gwladys Lengaigne Bruno Cavallier Wilfrid Boireau Virginie Blondeau-Patissier Integrated Love Wave Device Dedicated to Biomolecular Interactions Measurements in Aqueous Media Sensors Love waves SAW resonators Biosensor BSA adsorption detection |
| title | Integrated Love Wave Device Dedicated to Biomolecular Interactions Measurements in Aqueous Media |
| title_full | Integrated Love Wave Device Dedicated to Biomolecular Interactions Measurements in Aqueous Media |
| title_fullStr | Integrated Love Wave Device Dedicated to Biomolecular Interactions Measurements in Aqueous Media |
| title_full_unstemmed | Integrated Love Wave Device Dedicated to Biomolecular Interactions Measurements in Aqueous Media |
| title_short | Integrated Love Wave Device Dedicated to Biomolecular Interactions Measurements in Aqueous Media |
| title_sort | integrated love wave device dedicated to biomolecular interactions measurements in aqueous media |
| topic | Love waves SAW resonators Biosensor BSA adsorption detection |
| url | http://www.mdpi.com/1424-8220/7/9/1992/ |
| work_keys_str_mv | AT sylvainballandras integratedlovewavedevicededicatedtobiomolecularinteractionsmeasurementsinaqueousmedia AT gillesmartin integratedlovewavedevicededicatedtobiomolecularinteractionsmeasurementsinaqueousmedia AT williamdaniau integratedlovewavedevicededicatedtobiomolecularinteractionsmeasurementsinaqueousmedia AT gwladyslengaigne integratedlovewavedevicededicatedtobiomolecularinteractionsmeasurementsinaqueousmedia AT brunocavallier integratedlovewavedevicededicatedtobiomolecularinteractionsmeasurementsinaqueousmedia AT wilfridboireau integratedlovewavedevicededicatedtobiomolecularinteractionsmeasurementsinaqueousmedia AT virginieblondeaupatissier integratedlovewavedevicededicatedtobiomolecularinteractionsmeasurementsinaqueousmedia |