Aging beyond menopause selectively decreases CD8+ T cell numbers but enhances cytotoxic activity in the human endometrium
Abstract Background Regulation of endometrial (EM) CD8+ T cells, which provide protection through cell-mediated cytotoxicity, is essential for successful reproduction, and protection against sexually transmitted infections and potential tumors. We have previously demonstrated that EM CD8+ T cell cyt...
Main Authors: | Zheng Shen, Mickey V. Patel, Marta Rodriguez-Garcia, Charles R. Wira |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-11-01
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Series: | Immunity & Ageing |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12979-022-00312-w |
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