COVID‑19 in pregnant women in South Africa: A retrospective review
Background. The majority of maternal deaths in South Africa (SA) occur as a result of non-pregnancy-related infections (NPRI). Pregnancy is a known risk factor in severe COVID‑19, increasing the burden of NPRI in SA. In this study, we describe the prevalence, profile and clinical outcomes of pregna...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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South African Medical Association
2022-12-01
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| Series: | South African Medical Journal |
| Subjects: | |
| Online Access: | https://samajournals.co.za/index.php/samj/article/view/543 |
| _version_ | 1797369748524105728 |
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| author | S Bhoora J Zamparini N Odell L Murray G Balie N Sanyika K Mall T Ramdin A Mahomed L Chauke |
| author_facet | S Bhoora J Zamparini N Odell L Murray G Balie N Sanyika K Mall T Ramdin A Mahomed L Chauke |
| author_sort | S Bhoora |
| collection | DOAJ |
| description |
Background. The majority of maternal deaths in South Africa (SA) occur as a result of non-pregnancy-related infections (NPRI). Pregnancy is a known risk factor in severe COVID‑19, increasing the burden of NPRI in SA. In this study, we describe the prevalence, profile and clinical outcomes of pregnant women with COVID‑19 admitted to a tertiary facility.
Objectives. To describe the prevalence, profile and clinical outcomes of pregnant women with COVID‑19 admitted to a tertiary facility in Gauteng, SA.
Methods. We performed a retrospective review of all pregnant women with COVID‑19 admitted to Charlotte Maxeke Johannesburg
Academic Hospital between 6 March and 30 August 2020. Data collected included demographics, medical history, obstetric history, clinical findings and laboratory variables. Outcomes assessed were mortality, admission to intensive care unit (ICU), symptomatic v. asymptomatic disease, maternal and fetal outcome and mode of delivery.
Results. A total of 204 pregnant women were included in the study. Of these, 33 (16.2%) women were critically ill, with 21 (10.3%) admitted to the ICU and 3 (1.5%) deaths related to COVID‑19. The median gestational age was 37 weeks and median birthweight 2 940 g. Sixty-seven women (33%) were HIV-positive, in keeping with national statistics regarding HIV in pregnancy. Caesarean section was the most common mode of delivery (n=105, 60%). However, no women underwent caesarean section for indications related to COVID‑19.
Conclusion. COVID‑19-related mortality in our cohort was higher than that seen internationally, likely due to differences in background maternal mortality rates and difficulty in accessing care.
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| first_indexed | 2024-03-08T17:51:23Z |
| format | Article |
| id | doaj.art-ad66d789888f4fb6abe23fd2684c180b |
| institution | Directory Open Access Journal |
| issn | 0256-9574 2078-5135 |
| language | English |
| last_indexed | 2024-03-08T17:51:23Z |
| publishDate | 2022-12-01 |
| publisher | South African Medical Association |
| record_format | Article |
| series | South African Medical Journal |
| spelling | doaj.art-ad66d789888f4fb6abe23fd2684c180b2024-01-02T07:54:51ZengSouth African Medical AssociationSouth African Medical Journal0256-95742078-51352022-12-011121210.7196/SAMJ.2022.v112i12.16552COVID‑19 in pregnant women in South Africa: A retrospective reviewS Bhoora0J Zamparini1N Odell2L Murray3G Balie4N Sanyika5K Mall6T Ramdin7A Mahomed8L Chauke9Department of Obstetrics and Gynaecology ,University of the Witwatersrand, Johannesburg, South Africa; Department of Obstetrics and Gynaecology, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDepartment of Internal Medicine, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDepartment of Obstetrics and Gynaecology ,University of the Witwatersrand, Johannesburg, South Africa; Department of Obstetrics and Gynaecology, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDivision of Infectious Diseases, Department of Internal Medicine, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDepartment of Obstetrics and Gynaecology ,University of the Witwatersrand, Johannesburg, South Africa 2 Department of Obstetrics and Gynaecology, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDepartment of Internal Medicine, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDepartment of Internal Medicine, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDepartment of Paediatrics and Child Health, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDepartment of Internal Medicine, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South AfricaDepartment of Obstetrics and Gynaecology ,University of the Witwatersrand, Johannesburg, South Africa Background. The majority of maternal deaths in South Africa (SA) occur as a result of non-pregnancy-related infections (NPRI). Pregnancy is a known risk factor in severe COVID‑19, increasing the burden of NPRI in SA. In this study, we describe the prevalence, profile and clinical outcomes of pregnant women with COVID‑19 admitted to a tertiary facility. Objectives. To describe the prevalence, profile and clinical outcomes of pregnant women with COVID‑19 admitted to a tertiary facility in Gauteng, SA. Methods. We performed a retrospective review of all pregnant women with COVID‑19 admitted to Charlotte Maxeke Johannesburg Academic Hospital between 6 March and 30 August 2020. Data collected included demographics, medical history, obstetric history, clinical findings and laboratory variables. Outcomes assessed were mortality, admission to intensive care unit (ICU), symptomatic v. asymptomatic disease, maternal and fetal outcome and mode of delivery. Results. A total of 204 pregnant women were included in the study. Of these, 33 (16.2%) women were critically ill, with 21 (10.3%) admitted to the ICU and 3 (1.5%) deaths related to COVID‑19. The median gestational age was 37 weeks and median birthweight 2 940 g. Sixty-seven women (33%) were HIV-positive, in keeping with national statistics regarding HIV in pregnancy. Caesarean section was the most common mode of delivery (n=105, 60%). However, no women underwent caesarean section for indications related to COVID‑19. Conclusion. COVID‑19-related mortality in our cohort was higher than that seen internationally, likely due to differences in background maternal mortality rates and difficulty in accessing care. https://samajournals.co.za/index.php/samj/article/view/543COVID-19Obstetrics |
| spellingShingle | S Bhoora J Zamparini N Odell L Murray G Balie N Sanyika K Mall T Ramdin A Mahomed L Chauke COVID‑19 in pregnant women in South Africa: A retrospective review South African Medical Journal COVID-19 Obstetrics |
| title | COVID‑19 in pregnant women in South Africa: A retrospective review |
| title_full | COVID‑19 in pregnant women in South Africa: A retrospective review |
| title_fullStr | COVID‑19 in pregnant women in South Africa: A retrospective review |
| title_full_unstemmed | COVID‑19 in pregnant women in South Africa: A retrospective review |
| title_short | COVID‑19 in pregnant women in South Africa: A retrospective review |
| title_sort | covid 19 in pregnant women in south africa a retrospective review |
| topic | COVID-19 Obstetrics |
| url | https://samajournals.co.za/index.php/samj/article/view/543 |
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