The association between dietary inflammatory index with endometriosis: NHANES 2001-2006.
Endometriosis is a common chronic inflammatory and estrogen-dependent disease that mostly affects people of childbearing age. The dietary inflammatory index (DII) is a novel instrument for assessing the overall inflammatory potential of diet. However, no studies have shown the relationship between D...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0283216 |
| _version_ | 1827948713719365632 |
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| author | Pan-Wei Hu Bi-Rong Yang Xiao-Le Zhang Xiao-Tong Yan Juan-Juan Ma Cong Qi Guo-Jing Jiang |
| author_facet | Pan-Wei Hu Bi-Rong Yang Xiao-Le Zhang Xiao-Tong Yan Juan-Juan Ma Cong Qi Guo-Jing Jiang |
| author_sort | Pan-Wei Hu |
| collection | DOAJ |
| description | Endometriosis is a common chronic inflammatory and estrogen-dependent disease that mostly affects people of childbearing age. The dietary inflammatory index (DII) is a novel instrument for assessing the overall inflammatory potential of diet. However, no studies have shown the relationship between DII and endometriosis to date. This study aimed to elucidate the relationship between DII and endometriosis. Data were acquired from the National Health and Nutrition Examination Survey (NHANES) 2001-2006. DII was calculated using an inbuilt function in the R package. Relevant patient information was obtained through a questionnaire containing their gynecological history. Based on an endometriosis questionnaire survey, those participants who answered yes were considered cases (with endometriosis), and participants who answered no were considered as controls (without endometriosis) group. Multivariate weighted logistic regression was applied to examine the correlation between DII and endometriosis. Subgroup analysis and smoothing curve between DII and endometriosis were conducted in a further investigation. Compared to the control group, patients were prone to having a higher DII (P = 0.014). Adjusted multivariate regression models showed that DII was positively correlated with the incidence of endometriosis (P < 0.05). Analysis of subgroups revealed no significant heterogeneity. In middle-aged and older women (age ≥ 35 years), the smoothing curve fitting analysis results demonstrated a non-linear relationship between DII and the prevalence of endometriosis. Therefore, using DII as an indicator of dietary-related inflammation may help to provide new insight into the role of diet in the prevention and management of endometriosis. |
| first_indexed | 2024-04-09T12:58:26Z |
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| id | doaj.art-ad68f0ced88e43108403ecd96dc2261a |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-09T12:58:26Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-ad68f0ced88e43108403ecd96dc2261a2023-05-13T05:31:38ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01184e028321610.1371/journal.pone.0283216The association between dietary inflammatory index with endometriosis: NHANES 2001-2006.Pan-Wei HuBi-Rong YangXiao-Le ZhangXiao-Tong YanJuan-Juan MaCong QiGuo-Jing JiangEndometriosis is a common chronic inflammatory and estrogen-dependent disease that mostly affects people of childbearing age. The dietary inflammatory index (DII) is a novel instrument for assessing the overall inflammatory potential of diet. However, no studies have shown the relationship between DII and endometriosis to date. This study aimed to elucidate the relationship between DII and endometriosis. Data were acquired from the National Health and Nutrition Examination Survey (NHANES) 2001-2006. DII was calculated using an inbuilt function in the R package. Relevant patient information was obtained through a questionnaire containing their gynecological history. Based on an endometriosis questionnaire survey, those participants who answered yes were considered cases (with endometriosis), and participants who answered no were considered as controls (without endometriosis) group. Multivariate weighted logistic regression was applied to examine the correlation between DII and endometriosis. Subgroup analysis and smoothing curve between DII and endometriosis were conducted in a further investigation. Compared to the control group, patients were prone to having a higher DII (P = 0.014). Adjusted multivariate regression models showed that DII was positively correlated with the incidence of endometriosis (P < 0.05). Analysis of subgroups revealed no significant heterogeneity. In middle-aged and older women (age ≥ 35 years), the smoothing curve fitting analysis results demonstrated a non-linear relationship between DII and the prevalence of endometriosis. Therefore, using DII as an indicator of dietary-related inflammation may help to provide new insight into the role of diet in the prevention and management of endometriosis.https://doi.org/10.1371/journal.pone.0283216 |
| spellingShingle | Pan-Wei Hu Bi-Rong Yang Xiao-Le Zhang Xiao-Tong Yan Juan-Juan Ma Cong Qi Guo-Jing Jiang The association between dietary inflammatory index with endometriosis: NHANES 2001-2006. PLoS ONE |
| title | The association between dietary inflammatory index with endometriosis: NHANES 2001-2006. |
| title_full | The association between dietary inflammatory index with endometriosis: NHANES 2001-2006. |
| title_fullStr | The association between dietary inflammatory index with endometriosis: NHANES 2001-2006. |
| title_full_unstemmed | The association between dietary inflammatory index with endometriosis: NHANES 2001-2006. |
| title_short | The association between dietary inflammatory index with endometriosis: NHANES 2001-2006. |
| title_sort | association between dietary inflammatory index with endometriosis nhanes 2001 2006 |
| url | https://doi.org/10.1371/journal.pone.0283216 |
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