Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor β1

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor β1

Abstract Background Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is the myofibroblast, and fibr...

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Bibliographic Details
Main Authors: J. S. Lawson, H. M. Syme, C. P. D. Wheeler-Jones, J. Elliott
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Veterinary Research
Subjects:
CKD
Cats
Renal fibrosis
Myofibroblast
Online Access:http://link.springer.com/article/10.1186/s12917-018-1387-2

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