Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection

Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection

Middle East respiratory syndrome (MERS) continues to raise worldwide concerns due to its pandemic potential. Increased MERS cases and no licensed MERS vaccines highlight the need to develop safe and effective vaccines against MERS. We have previously demonstrated that a receptor-binding domain (RBD)...

Bibliografski detalji
Glavni autori:	Yufei Wang, Wanbo Tai, Jie Yang, Guangyu Zhao, Shihui Sun, Chien-Te K. Tseng, Shibo Jiang, Yusen Zhou, Lanying Du, Jimin Gao
Format:	Članak
Jezik:	English
Izdano:	Taylor & Francis Group 2017-07-01
Serija:	Human Vaccines & Immunotherapeutics
Teme:	hdpp4-transgenic mice mers-cov neutralizing antibodies optimal immunogen dosage optimal immunization interval protection receptor-binding domain
Online pristup:	http://dx.doi.org/10.1080/21645515.2017.1296994

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