The Pharmacological Efficacy of Baicalin in Inflammatory Diseases
Baicalin is one of the most abundant flavonoids found in the dried roots of <i>Scutellaria baicalensis</i> Georgi (SBG) belonging to the genus <i>Scutellaria</i>. While baicalin is demonstrated to have anti-inflammatory, antiviral, antitumor, antibacterial, anticonvulsant, an...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-05-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/11/9317 |
| Summary: | Baicalin is one of the most abundant flavonoids found in the dried roots of <i>Scutellaria baicalensis</i> Georgi (SBG) belonging to the genus <i>Scutellaria</i>. While baicalin is demonstrated to have anti-inflammatory, antiviral, antitumor, antibacterial, anticonvulsant, antioxidant, hepatoprotective, and neuroprotective effects, its low hydrophilicity and lipophilicity limit the bioavailability and pharmacological functions. Therefore, an in-depth study of baicalin’s bioavailability and pharmacokinetics contributes to laying the theoretical foundation for applied research in disease treatment. In this view, the physicochemical properties and anti-inflammatory activity of baicalin are summarized in terms of bioavailability, drug interaction, and inflammatory conditions. |
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| ISSN: | 1661-6596 1422-0067 |