In vitro and in vivo anti-schistosomal activity of the alkylphospholipid analog edelfosine.
BACKGROUND: Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma. Five species of Schistosoma are known to infect humans, out of which S. haematobium is the most prevalent, causing the chronic parasitic disease schistosomiasis that still represents a major problem of...
Main Authors: | Edward Yepes, Rubén E Varela-M, Julio López-Abán, El Habib Dakir, Faustino Mollinedo, Antonio Muro |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4193788?pdf=render |
Similar Items
-
Erratum: In vitro and in vivo anti-schistosomal activity of the alkylphospholipid analog edelfosine.
by: PLOS ONE Staff
Published: (2015-01-01) -
Antitumor activity of alkylphospholipid edelfosine in prostate cancer models and endoplasmic reticulum targeting
by: EL-Habib Dakir, et al.
Published: (2023-11-01) -
Mitochondrial Targeting Involving Cholesterol-Rich Lipid Rafts in the Mechanism of Action of the Antitumor Ether Lipid and Alkylphospholipid Analog Edelfosine
by: Faustino Mollinedo, et al.
Published: (2021-05-01) -
Direct Endoplasmic Reticulum Targeting by the Selective Alkylphospholipid Analog and Antitumor Ether Lipid Edelfosine as a Therapeutic Approach in Pancreatic Cancer
by: Faustino Mollinedo, et al.
Published: (2021-08-01) -
Induction of Apoptosis in Human Pancreatic Cancer Stem Cells by the Endoplasmic Reticulum-Targeted Alkylphospholipid Analog Edelfosine and Potentiation by Autophagy Inhibition
by: Consuelo Gajate, et al.
Published: (2021-12-01)