PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY
ABSTRACT Objectives: To evaluate the effectiveness of aspirin as prophylaxis for deep venous thrombosis (DVT) in patients undergoing total hip arthroplasty (THA), and to analyze the incidence of bleeding during the post-operative period. Methods: This prospective study carried out in 2017 consiste...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Ortopedia e Traumatologia
2018-04-01
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| Series: | Acta Ortopédica Brasileira |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522018000200086&tlng=en |
| _version_ | 1818973029573591040 |
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| author | RAUL CARNEIRO LINS EPITÁCIO LEITE ROLIM FILHO FERNANDO DE SANTA CRUZ OLIVEIRA SAULO MONTEIRO DOS SANTOS TALE LUCAS VIEIRA ROLIM FLÁVIO KREIMER |
| author_facet | RAUL CARNEIRO LINS EPITÁCIO LEITE ROLIM FILHO FERNANDO DE SANTA CRUZ OLIVEIRA SAULO MONTEIRO DOS SANTOS TALE LUCAS VIEIRA ROLIM FLÁVIO KREIMER |
| author_sort | RAUL CARNEIRO LINS |
| collection | DOAJ |
| description | ABSTRACT Objectives: To evaluate the effectiveness of aspirin as prophylaxis for deep venous thrombosis (DVT) in patients undergoing total hip arthroplasty (THA), and to analyze the incidence of bleeding during the post-operative period. Methods: This prospective study carried out in 2017 consisted of 37 patients indicated for THA with high risk for DVT. Immediately after the procedure, aspirin, elastic compression socks and early deambulation were initiated. Doppler ultrasound was performed in the legs 6 days and 6 weeks post-procedure to rule out venous thromboembolism. Hematometric variables and clinical criteria were used to detect bleeding. Results: The incidence of VTE (venous thromboembolism) 6 days post-procedure was 21.6%. By 6 weeks post-procedure, it dropped to 8.1%, (p = 0.102). Only 2.7% were diagnosed with VTE, 6 days and also 6 weeks post-procedure. Within the immediate postoperative period, hemoglobin was lower (p < 0.001), in contrast to 6 weeks after surgery, when it returned to baseline levels. Conclusion: Aspirin was an effective chemical prophylaxis for venous thromboembolism in high-risk patients who underwent THA. There was no clinical record of postoperative bleeding and hematometric levels suggested that there was no chronic bleeding. Level of Evidence II; Prospective study. |
| first_indexed | 2024-12-20T15:17:40Z |
| format | Article |
| id | doaj.art-ad7507ef8cad448eb4de721ee51793cb |
| institution | Directory Open Access Journal |
| issn | 1413-7852 |
| language | English |
| last_indexed | 2024-12-20T15:17:40Z |
| publishDate | 2018-04-01 |
| publisher | Sociedade Brasileira de Ortopedia e Traumatologia |
| record_format | Article |
| series | Acta Ortopédica Brasileira |
| spelling | doaj.art-ad7507ef8cad448eb4de721ee51793cb2022-12-21T19:36:08ZengSociedade Brasileira de Ortopedia e TraumatologiaActa Ortopédica Brasileira1413-78522018-04-01262869010.1590/1413-785220182602187265PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTYRAUL CARNEIRO LINShttps://orcid.org/0000-0001-5133-2118EPITÁCIO LEITE ROLIM FILHOhttps://orcid.org/0000-0003-1305-6620FERNANDO DE SANTA CRUZ OLIVEIRAhttps://orcid.org/0000-0002-3178-1036SAULO MONTEIRO DOS SANTOShttps://orcid.org/0000-0002-0436-2012TALE LUCAS VIEIRA ROLIMhttps://orcid.org/0000-0001-8450-9805FLÁVIO KREIMERhttps://orcid.org/0000-0001-6164-9987ABSTRACT Objectives: To evaluate the effectiveness of aspirin as prophylaxis for deep venous thrombosis (DVT) in patients undergoing total hip arthroplasty (THA), and to analyze the incidence of bleeding during the post-operative period. Methods: This prospective study carried out in 2017 consisted of 37 patients indicated for THA with high risk for DVT. Immediately after the procedure, aspirin, elastic compression socks and early deambulation were initiated. Doppler ultrasound was performed in the legs 6 days and 6 weeks post-procedure to rule out venous thromboembolism. Hematometric variables and clinical criteria were used to detect bleeding. Results: The incidence of VTE (venous thromboembolism) 6 days post-procedure was 21.6%. By 6 weeks post-procedure, it dropped to 8.1%, (p = 0.102). Only 2.7% were diagnosed with VTE, 6 days and also 6 weeks post-procedure. Within the immediate postoperative period, hemoglobin was lower (p < 0.001), in contrast to 6 weeks after surgery, when it returned to baseline levels. Conclusion: Aspirin was an effective chemical prophylaxis for venous thromboembolism in high-risk patients who underwent THA. There was no clinical record of postoperative bleeding and hematometric levels suggested that there was no chronic bleeding. Level of Evidence II; Prospective study.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522018000200086&tlng=enArthroplasty, replacement, hipAspirinVenous thrombosis/prevention & control |
| spellingShingle | RAUL CARNEIRO LINS EPITÁCIO LEITE ROLIM FILHO FERNANDO DE SANTA CRUZ OLIVEIRA SAULO MONTEIRO DOS SANTOS TALE LUCAS VIEIRA ROLIM FLÁVIO KREIMER PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY Acta Ortopédica Brasileira Arthroplasty, replacement, hip Aspirin Venous thrombosis/prevention & control |
| title | PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY |
| title_full | PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY |
| title_fullStr | PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY |
| title_full_unstemmed | PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY |
| title_short | PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY |
| title_sort | prospective study of aspirin for thromboembolism prophylaxis in total hip arthroplasty |
| topic | Arthroplasty, replacement, hip Aspirin Venous thrombosis/prevention & control |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522018000200086&tlng=en |
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