RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression
Interleukin-17 (IL-17)-producing helper T cells (Th17 cells) play an important role in autoimmune diseases. However, not all Th17 cells induce tissue inflammation or autoimmunity. Th17 cells require IL-23 receptor (IL-23R) signaling to become pathogenic. The transcriptional mechanisms controlling th...
| Auteurs principaux: | , , , , , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Elsevier
2016-07-01
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| Collection: | Cell Reports |
| Sujets: | |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S221112471630701X |