RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression

RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression

Interleukin-17 (IL-17)-producing helper T cells (Th17 cells) play an important role in autoimmune diseases. However, not all Th17 cells induce tissue inflammation or autoimmunity. Th17 cells require IL-23 receptor (IL-23R) signaling to become pathogenic. The transcriptional mechanisms controlling th...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Gerd Meyer zu Horste, Chuan Wu, Chao Wang, Le Cong, Mathias Pawlak, Youjin Lee, Wassim Elyaman, Sheng Xiao, Aviv Regev, Vijay K. Kuchroo
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	Elsevier 2016-07-01
Σειρά:	Cell Reports
Θέματα:	Th17 cells pathogenicity IL-23R RBPJ Notch
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S221112471630701X

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ανά: Bernd M. Gahr, κ.ά.
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ανά: Shuaishuai Chen, κ.ά.
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ανά: Fabrine Sales Massafera Tristão, κ.ά.
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ανά: Yong-Hong Zhang, κ.ά.
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Έκδοση: (2024-09-01)

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Έκδοση: (2022-09-01)

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ανά: M.V. Stoikevych, κ.ά.
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ανά: Victoria Navarro-Compán, κ.ά.
Έκδοση: (2023-08-01)

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Έκδοση: (2023-11-01)

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ανά: Caner Cam, κ.ά.
Έκδοση: (2016-08-01)

Current perspective on the role of the interleukin-23/interleukin-17 axis in inflammation and disease (chronic arthritis and psoriasis)
ανά: Cauli A, κ.ά.
Έκδοση: (2015-10-01)

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ανά: Jamison J. Grailer, κ.ά.
Έκδοση: (2013-01-01)

IL-15 negatively regulates curdlan-induced IL-23 production by human monocyte-derived dendritic cells and subsequent Th17 response
ανά: Ahmet Eken, κ.ά.
Έκδοση: (2019-11-01)

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ανά: Ruth Rodríguez‐Montaño, κ.ά.
Έκδοση: (2025-02-01)

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ανά: Hanieh Kolahdooz, κ.ά.
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ανά: Hulya Deveci, κ.ά.
Έκδοση: (2020-01-01)

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Έκδοση: (2024-10-01)

Expression of il-23/th17 pathway in a murine model of coxsackie virus b3-induced viral myocarditis
ανά: Kong Qing, κ.ά.
Έκδοση: (2011-06-01)

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ανά: Luca Potestio, κ.ά.
Έκδοση: (2024-07-01)

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ανά: Gloria Pastor-Fernández, κ.ά.
Έκδοση: (2020-09-01)

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ανά: Saaya Yoshida, κ.ά.
Έκδοση: (2020-04-01)

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ανά: Potestio L, κ.ά.
Έκδοση: (2024-04-01)

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ανά: Maria Ganeva, κ.ά.
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