Novel Betacoronavirus in Dromedaries of the Middle East, 2013
In 2013, a novel betacoronavirus was identified in fecal samples from dromedaries in Dubai, United Arab Emirates. Antibodies against the recombinant nucleocapsid protein of the virus, which we named dromedary camel coronavirus (DcCoV) UAE-HKU23, were detected in 52% of 59 dromedary serum samples tes...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2014-04-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/20/4/13-1769_article |
| _version_ | 1811263779126640640 |
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| author | Patrick C.Y. Woo Susanna K.P. Lau Ulrich Wernery Emily Y.M. Wong Alan K.L. Tsang Bobby Johnson Cyril C.Y. Yip Candy C.Y. Lau Saritha Sivakumar Jian-Piao Cai Rachel Y.Y. Fan Kwok-Hung Chan Ringu Mareena Kwok-Yung Yuen |
| author_facet | Patrick C.Y. Woo Susanna K.P. Lau Ulrich Wernery Emily Y.M. Wong Alan K.L. Tsang Bobby Johnson Cyril C.Y. Yip Candy C.Y. Lau Saritha Sivakumar Jian-Piao Cai Rachel Y.Y. Fan Kwok-Hung Chan Ringu Mareena Kwok-Yung Yuen |
| author_sort | Patrick C.Y. Woo |
| collection | DOAJ |
| description | In 2013, a novel betacoronavirus was identified in fecal samples from dromedaries in Dubai, United Arab Emirates. Antibodies against the recombinant nucleocapsid protein of the virus, which we named dromedary camel coronavirus (DcCoV) UAE-HKU23, were detected in 52% of 59 dromedary serum samples tested. In an analysis of 3 complete DcCoV UAE-HKU23 genomes, we identified the virus as a betacoronavirus in lineage A1. The DcCoV UAE-HKU23 genome has G+C contents; a general preference for G/C in the third position of codons; a cleavage site for spike protein; and a membrane protein of similar length to that of other betacoronavirus A1 members, to which DcCoV UAE-HKU23 is phylogenetically closely related. Along with this coronavirus, viruses of at least 8 other families have been found to infect camels. Because camels have a close association with humans, continuous surveillance should be conducted to understand the potential for virus emergence in camels and for virus transmission to humans. |
| first_indexed | 2024-04-12T19:51:22Z |
| format | Article |
| id | doaj.art-ad81ba6e43974f8982785772f56ba189 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-12T19:51:22Z |
| publishDate | 2014-04-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-ad81ba6e43974f8982785772f56ba1892022-12-22T03:18:49ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-04-0120456057210.3201/eid2004.131769Novel Betacoronavirus in Dromedaries of the Middle East, 2013Patrick C.Y. WooSusanna K.P. LauUlrich WerneryEmily Y.M. WongAlan K.L. TsangBobby JohnsonCyril C.Y. YipCandy C.Y. LauSaritha SivakumarJian-Piao CaiRachel Y.Y. FanKwok-Hung ChanRingu MareenaKwok-Yung YuenIn 2013, a novel betacoronavirus was identified in fecal samples from dromedaries in Dubai, United Arab Emirates. Antibodies against the recombinant nucleocapsid protein of the virus, which we named dromedary camel coronavirus (DcCoV) UAE-HKU23, were detected in 52% of 59 dromedary serum samples tested. In an analysis of 3 complete DcCoV UAE-HKU23 genomes, we identified the virus as a betacoronavirus in lineage A1. The DcCoV UAE-HKU23 genome has G+C contents; a general preference for G/C in the third position of codons; a cleavage site for spike protein; and a membrane protein of similar length to that of other betacoronavirus A1 members, to which DcCoV UAE-HKU23 is phylogenetically closely related. Along with this coronavirus, viruses of at least 8 other families have been found to infect camels. Because camels have a close association with humans, continuous surveillance should be conducted to understand the potential for virus emergence in camels and for virus transmission to humans.https://wwwnc.cdc.gov/eid/article/20/4/13-1769_articlecoronavirusdromedarycamelMiddle Eastbetacoronavirusdromedaries |
| spellingShingle | Patrick C.Y. Woo Susanna K.P. Lau Ulrich Wernery Emily Y.M. Wong Alan K.L. Tsang Bobby Johnson Cyril C.Y. Yip Candy C.Y. Lau Saritha Sivakumar Jian-Piao Cai Rachel Y.Y. Fan Kwok-Hung Chan Ringu Mareena Kwok-Yung Yuen Novel Betacoronavirus in Dromedaries of the Middle East, 2013 Emerging Infectious Diseases coronavirus dromedary camel Middle East betacoronavirus dromedaries |
| title | Novel Betacoronavirus in Dromedaries of the Middle East, 2013 |
| title_full | Novel Betacoronavirus in Dromedaries of the Middle East, 2013 |
| title_fullStr | Novel Betacoronavirus in Dromedaries of the Middle East, 2013 |
| title_full_unstemmed | Novel Betacoronavirus in Dromedaries of the Middle East, 2013 |
| title_short | Novel Betacoronavirus in Dromedaries of the Middle East, 2013 |
| title_sort | novel betacoronavirus in dromedaries of the middle east 2013 |
| topic | coronavirus dromedary camel Middle East betacoronavirus dromedaries |
| url | https://wwwnc.cdc.gov/eid/article/20/4/13-1769_article |
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