Lung Mammary Metastases but Not Primary Tumors Induce Accumulation of Atypical Large Platelets and Their Chemokine Expression
Summary: The tumor microenvironment (TME) at the metastatic site consists of multiple components with considerable cellular heterogeneity. To test whether endothelial cells (ECs) associated with lung metastases express a distinct gene expression program that promotes metastatic growth, we isolated C...
Main Authors: | Wei Zheng, Hui Zhang, Dejian Zhao, Jinghang Zhang, Jeffrey W. Pollard |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-11-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719313166 |
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