β-Alanine Enhances Brain and Muscle Carnosine Levels in Broiler Chicks
Carnosine and its methylated derivative anserine are dipeptides present in high levels in chicken muscles. They are antioxidants and putative neurotransmitters. If administration of β-alanine, one of the constituents of carnosine, could increase levels of these dipeptides in the brain and muscles,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Japan Poultry Science Association
2012-10-01
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| Series: | The Journal of Poultry Science |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/49/4/49_0110165/_pdf/-char/en |
| _version_ | 1797816203003035648 |
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| author | Shozo Tomonaga Mitsuhito Matsumoto Mitsuhiro Furuse |
| author_facet | Shozo Tomonaga Mitsuhito Matsumoto Mitsuhiro Furuse |
| author_sort | Shozo Tomonaga |
| collection | DOAJ |
| description | Carnosine and its methylated derivative anserine are dipeptides present in high levels in chicken muscles. They are antioxidants and putative neurotransmitters. If administration of β-alanine, one of the constituents of carnosine, could increase levels of these dipeptides in the brain and muscles, it may improve brain function and increase commercial values of the chicken meat. In the present study, we investigated whether orally administered β-alanine could increase these dipeptide levels in the brain, Musculus pectoralis superficialis, and plasma in broiler chicks. Broilers (2 days old) were given oral doses of β-alanine (0.176, 0.88, 4.4 and 22 mmol/kg) twice a day for 5 days. Carnosine levels were dose-dependently increased in the brain, Musculus pectoralis superficialis, and plasma while no influence of anserine was detected. These results suggest that supplemental β-alanine could be effective in increasing carnosine levels in the brain and muscle of broiler chicks. |
| first_indexed | 2024-03-13T08:34:13Z |
| format | Article |
| id | doaj.art-ad857cfe0146479e8aa247f16d8e9b27 |
| institution | Directory Open Access Journal |
| issn | 1346-7395 1349-0486 |
| language | English |
| last_indexed | 2024-03-13T08:34:13Z |
| publishDate | 2012-10-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj.art-ad857cfe0146479e8aa247f16d8e9b272023-05-31T01:20:34ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862012-10-0149430831210.2141/jpsa.0110165jpsaβ-Alanine Enhances Brain and Muscle Carnosine Levels in Broiler ChicksShozo Tomonaga0Mitsuhito Matsumoto1Mitsuhiro Furuse2Laboratory of Regulation in Metabolism and Behavior, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, JapanLivestock and Grassland Research Division, NARO Kyushu Okinawa Agricultural Research Center, JapanLaboratory of Regulation in Metabolism and Behavior, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, JapanCarnosine and its methylated derivative anserine are dipeptides present in high levels in chicken muscles. They are antioxidants and putative neurotransmitters. If administration of β-alanine, one of the constituents of carnosine, could increase levels of these dipeptides in the brain and muscles, it may improve brain function and increase commercial values of the chicken meat. In the present study, we investigated whether orally administered β-alanine could increase these dipeptide levels in the brain, Musculus pectoralis superficialis, and plasma in broiler chicks. Broilers (2 days old) were given oral doses of β-alanine (0.176, 0.88, 4.4 and 22 mmol/kg) twice a day for 5 days. Carnosine levels were dose-dependently increased in the brain, Musculus pectoralis superficialis, and plasma while no influence of anserine was detected. These results suggest that supplemental β-alanine could be effective in increasing carnosine levels in the brain and muscle of broiler chicks.https://www.jstage.jst.go.jp/article/jpsa/49/4/49_0110165/_pdf/-char/enβ-alaninebrainbroilercarnosinemuscle |
| spellingShingle | Shozo Tomonaga Mitsuhito Matsumoto Mitsuhiro Furuse β-Alanine Enhances Brain and Muscle Carnosine Levels in Broiler Chicks The Journal of Poultry Science β-alanine brain broiler carnosine muscle |
| title | β-Alanine Enhances Brain and Muscle Carnosine Levels in Broiler Chicks |
| title_full | β-Alanine Enhances Brain and Muscle Carnosine Levels in Broiler Chicks |
| title_fullStr | β-Alanine Enhances Brain and Muscle Carnosine Levels in Broiler Chicks |
| title_full_unstemmed | β-Alanine Enhances Brain and Muscle Carnosine Levels in Broiler Chicks |
| title_short | β-Alanine Enhances Brain and Muscle Carnosine Levels in Broiler Chicks |
| title_sort | β alanine enhances brain and muscle carnosine levels in broiler chicks |
| topic | β-alanine brain broiler carnosine muscle |
| url | https://www.jstage.jst.go.jp/article/jpsa/49/4/49_0110165/_pdf/-char/en |
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