Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD)
Abstract Children with attention deficit-hyperactivity disorder (ADHD) have impaired hot and cold executive functions, which is thought to be related to impaired ventromedial and dorsolateral prefrontal cortex (vmPFC and dlPFC) functions. The present study aimed to assess the impact concurrent stimu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-03-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-57920-3 |
| _version_ | 1797233613676216320 |
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| author | Vahid Nejati Mahshid Dehghan Shahriar Shahidi Reza Estaji Michael A. Nitsche |
| author_facet | Vahid Nejati Mahshid Dehghan Shahriar Shahidi Reza Estaji Michael A. Nitsche |
| author_sort | Vahid Nejati |
| collection | DOAJ |
| description | Abstract Children with attention deficit-hyperactivity disorder (ADHD) have impaired hot and cold executive functions, which is thought to be related to impaired ventromedial and dorsolateral prefrontal cortex (vmPFC and dlPFC) functions. The present study aimed to assess the impact concurrent stimulation of dlPFC and vmPFC through transcranial random noise stimulation (tRNS), a non-invasive brain stimulation tool which enhances cortical excitability via application of alternating sinusoidal currents with random frequencies and amplitudes over the respective target regions on hot and cold executive functions. Eighteen children with ADHD received real and sham tRNS over the left dlPFC and the right vmPFC in two sessions with one week interval. The participants performed Circle Tracing, Go/No-Go, Wisconsin Card Sorting, and Balloon Analogue Risk Tasks during stimulation in each session. The results showed improved ongoing inhibition, prepotent inhibition, working memory, and decision making, but not set-shifting performance, during real, as compared to sham stimulation. This indicates that simultaneous stimulation of the dlPFC and the vmPFC improves hot and cold executive functions in children with ADHD. |
| first_indexed | 2024-04-24T16:18:57Z |
| format | Article |
| id | doaj.art-ad865aaf7cfb499ab6f09e395a186887 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-24T16:18:57Z |
| publishDate | 2024-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-ad865aaf7cfb499ab6f09e395a1868872024-03-31T11:20:13ZengNature PortfolioScientific Reports2045-23222024-03-0114111010.1038/s41598-024-57920-3Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD)Vahid Nejati0Mahshid Dehghan1Shahriar Shahidi2Reza Estaji3Michael A. Nitsche4Department of Psychology, Shahid Beheshti University TehranDepartment of Psychology, Shahid Beheshti University TehranDepartment of Psychology, Shahid Beheshti University TehranDepartment of Psychology, Shahid Beheshti University TehranDepartment of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human FactorsAbstract Children with attention deficit-hyperactivity disorder (ADHD) have impaired hot and cold executive functions, which is thought to be related to impaired ventromedial and dorsolateral prefrontal cortex (vmPFC and dlPFC) functions. The present study aimed to assess the impact concurrent stimulation of dlPFC and vmPFC through transcranial random noise stimulation (tRNS), a non-invasive brain stimulation tool which enhances cortical excitability via application of alternating sinusoidal currents with random frequencies and amplitudes over the respective target regions on hot and cold executive functions. Eighteen children with ADHD received real and sham tRNS over the left dlPFC and the right vmPFC in two sessions with one week interval. The participants performed Circle Tracing, Go/No-Go, Wisconsin Card Sorting, and Balloon Analogue Risk Tasks during stimulation in each session. The results showed improved ongoing inhibition, prepotent inhibition, working memory, and decision making, but not set-shifting performance, during real, as compared to sham stimulation. This indicates that simultaneous stimulation of the dlPFC and the vmPFC improves hot and cold executive functions in children with ADHD.https://doi.org/10.1038/s41598-024-57920-3Attention deficit-hyperactivity disorder (ADHD)Hot and cold executive functions ventromedial prefrontal cortex (vmPFC)Dorsolateral prefrontal cortex (dlPFC) transcranial random noise stimulation (tRNS) |
| spellingShingle | Vahid Nejati Mahshid Dehghan Shahriar Shahidi Reza Estaji Michael A. Nitsche Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD) Scientific Reports Attention deficit-hyperactivity disorder (ADHD) Hot and cold executive functions ventromedial prefrontal cortex (vmPFC) Dorsolateral prefrontal cortex (dlPFC) transcranial random noise stimulation (tRNS) |
| title | Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD) |
| title_full | Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD) |
| title_fullStr | Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD) |
| title_full_unstemmed | Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD) |
| title_short | Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD) |
| title_sort | transcranial random noise stimulation trns improves hot and cold executive functions in children with attention deficit hyperactivity disorder adhd |
| topic | Attention deficit-hyperactivity disorder (ADHD) Hot and cold executive functions ventromedial prefrontal cortex (vmPFC) Dorsolateral prefrontal cortex (dlPFC) transcranial random noise stimulation (tRNS) |
| url | https://doi.org/10.1038/s41598-024-57920-3 |
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