The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit?
We report a 75-year-old man with septic shock induced by ventilator-associated pneumonia caused by multiple drug-resistant Acinetobacter baumannii and catheter-related infection by vancomycin-resistant enterococci. He failed to respond to the initial management, including antibiotics (linezolid, imi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM)
2008-09-01
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| Series: | International Journal of Gerontology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873959808700504 |
| _version_ | 1818494705439080448 |
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| author | Po-Chin Chi Chien-Liang Wu Chung-Lieh Hung Yu-Ling Weng Ching-Chi Lin Shih-Yi Lee |
| author_facet | Po-Chin Chi Chien-Liang Wu Chung-Lieh Hung Yu-Ling Weng Ching-Chi Lin Shih-Yi Lee |
| author_sort | Po-Chin Chi |
| collection | DOAJ |
| description | We report a 75-year-old man with septic shock induced by ventilator-associated pneumonia caused by multiple drug-resistant Acinetobacter baumannii and catheter-related infection by vancomycin-resistant enterococci. He failed to respond to the initial management, including antibiotics (linezolid, imipenem, sulbactam and colistin) and hemodynamic-guided fluid challenge. However, his condition improved dramatically after the antibiotic regimen was changed to tigecycline and ceftazidime. In addition to the superiority of the antibacterial effect of tigecycline, fluid control can be achieved more easily while using a single antibiotic instead of multiple drugs, which is also important for care of a critically ill elderly man with compromised cardiorespiratory or renal function. Here, we present a patient infected with multiple drug-resistant pathogens, who improved clinically after being treated with tigecycline, to demonstrate the benefits of this antibiotic. |
| first_indexed | 2024-12-10T18:10:02Z |
| format | Article |
| id | doaj.art-ad87464437b84319a7f1f5581771dc4a |
| institution | Directory Open Access Journal |
| issn | 1873-9598 |
| language | English |
| last_indexed | 2024-12-10T18:10:02Z |
| publishDate | 2008-09-01 |
| publisher | Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM) |
| record_format | Article |
| series | International Journal of Gerontology |
| spelling | doaj.art-ad87464437b84319a7f1f5581771dc4a2022-12-22T01:38:30ZengTaiwan Society of Geriatric Emergency and Critical Medicine (TSGECM)International Journal of Gerontology1873-95982008-09-012312412710.1016/S1873-9598(08)70050-4The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit?Po-Chin Chi0Chien-Liang Wu1Chung-Lieh Hung2Yu-Ling Weng3Ching-Chi Lin4Shih-Yi Lee5Department of Internal Medicine, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Internal Medicine, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Internal Medicine, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Internal Medicine, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Internal Medicine, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Internal Medicine, Mackay Memorial Hospital, Taipei, TaiwanWe report a 75-year-old man with septic shock induced by ventilator-associated pneumonia caused by multiple drug-resistant Acinetobacter baumannii and catheter-related infection by vancomycin-resistant enterococci. He failed to respond to the initial management, including antibiotics (linezolid, imipenem, sulbactam and colistin) and hemodynamic-guided fluid challenge. However, his condition improved dramatically after the antibiotic regimen was changed to tigecycline and ceftazidime. In addition to the superiority of the antibacterial effect of tigecycline, fluid control can be achieved more easily while using a single antibiotic instead of multiple drugs, which is also important for care of a critically ill elderly man with compromised cardiorespiratory or renal function. Here, we present a patient infected with multiple drug-resistant pathogens, who improved clinically after being treated with tigecycline, to demonstrate the benefits of this antibiotic.http://www.sciencedirect.com/science/article/pii/S1873959808700504multiple antibacterial drug resistancetigecyclineventilator-associated pneumonia |
| spellingShingle | Po-Chin Chi Chien-Liang Wu Chung-Lieh Hung Yu-Ling Weng Ching-Chi Lin Shih-Yi Lee The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit? International Journal of Gerontology multiple antibacterial drug resistance tigecycline ventilator-associated pneumonia |
| title | The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit? |
| title_full | The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit? |
| title_fullStr | The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit? |
| title_full_unstemmed | The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit? |
| title_short | The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit? |
| title_sort | experience of a novel glycylcycline antibiotic for a patient with infection caused by multiple drug resistant pathogens what is the benefit |
| topic | multiple antibacterial drug resistance tigecycline ventilator-associated pneumonia |
| url | http://www.sciencedirect.com/science/article/pii/S1873959808700504 |
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