The inheritance of resistance alleles in multiple sclerosis.
Multiple sclerosis (MS) is a complex trait in which alleles at or near the class II loci HLA-DRB1 and HLA-DQB1 contribute significantly to genetic risk. HLA-DRB1*15 and HLA-DRB1*17-bearing haplotypes and interactions at the HLA-DRB1 locus increase risk of MS but it has taken large samples to identif...
Päätekijät: | , , , , , , , , , |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
Julkaistu: |
Public Library of Science (PLoS)
2007-09-01
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Sarja: | PLoS Genetics |
Linkit: | http://europepmc.org/articles/PMC1971120?pdf=render |