Layered double hydroxide nanostructures as drug-carriers in treatment of breast cancer
Breast cancer is a public health problem globally and is the most frequent cancer world wide. Currently, anti-inflammatory and anti-cancer drugs are of prime interest in treating some cancers especially breast cancer and have become an exciting challenge for researchers. The use of layered structure...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2022-04-01
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| Series: | Nanomedicine Journal |
| Subjects: | |
| Online Access: | https://nmj.mums.ac.ir/article_19917_6380f8c250ff43c1404740cd8a8c10f9.pdf |
| _version_ | 1819210479265906688 |
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| author | Kamram Hosseini Saiedeh Razi Soofiyani Reza Eghdam Zamiri Afsaneh Farjami Azita Dilmaghani Mehri Mahdavi Vahideh Tarhriz Vahid Yousefi |
| author_facet | Kamram Hosseini Saiedeh Razi Soofiyani Reza Eghdam Zamiri Afsaneh Farjami Azita Dilmaghani Mehri Mahdavi Vahideh Tarhriz Vahid Yousefi |
| author_sort | Kamram Hosseini |
| collection | DOAJ |
| description | Breast cancer is a public health problem globally and is the most frequent cancer world wide. Currently, anti-inflammatory and anti-cancer drugs are of prime interest in treating some cancers especially breast cancer and have become an exciting challenge for researchers. The use of layered structures consisting of anions and cations called layered double hydroxides (LDHs) has attracted the attention of many researchers in the field of biomedical and pharmaceuticals. LDHs-nanostructures can be used as drug carriers, especially anti-inflammatory and anti-cancer drugs to treat cancers. Thus, the LDHs should have a number of physicochemical properties to act as a desirable drug carrier. Among the primary factors to increase the efficiency of LDHs are their surface characteristics and size, number and type of ions, rapid clearance from the body after drug release, and non-toxicity. All of these properties make LDHs nano-carriers for carrying anti-inflammatory and anti-cancer drugs to treat a variety of cancers. Therefore, we focus on reviewing the nature of LDH nano-carriers and evaluating the desirable properties for drug delivery, drug loading methods into LDH and anti-inflammatory drug delivery methods, their potential applications in biomedical and their toxicity and antimicrobial effects in breast cancer. |
| first_indexed | 2024-12-23T06:11:50Z |
| format | Article |
| id | doaj.art-ad8f8194583d4dbaa46d0e883008220b |
| institution | Directory Open Access Journal |
| issn | 2322-3049 2322-5904 |
| language | English |
| last_indexed | 2024-12-23T06:11:50Z |
| publishDate | 2022-04-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Nanomedicine Journal |
| spelling | doaj.art-ad8f8194583d4dbaa46d0e883008220b2022-12-21T17:57:26ZengMashhad University of Medical SciencesNanomedicine Journal2322-30492322-59042022-04-01929510610.22038/nmj.2022.63097.166119917Layered double hydroxide nanostructures as drug-carriers in treatment of breast cancerKamram Hosseini0Saiedeh Razi Soofiyani1Reza Eghdam Zamiri2Afsaneh Farjami3Azita Dilmaghani4Mehri Mahdavi5Vahideh Tarhriz6Vahid Yousefi7Student Research Committee, Shiraz University of Medical Sciences, Shiraz, IranMolecular Medicine Research Center, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Radiation Oncology, Tabriz International Hospital, Tabriz, IranFood and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, IranFaculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, IranMolecular Medicine Research Center, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, IranMolecular Medicine Research Center, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, IranMolecular Medicine Research Center, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, IranBreast cancer is a public health problem globally and is the most frequent cancer world wide. Currently, anti-inflammatory and anti-cancer drugs are of prime interest in treating some cancers especially breast cancer and have become an exciting challenge for researchers. The use of layered structures consisting of anions and cations called layered double hydroxides (LDHs) has attracted the attention of many researchers in the field of biomedical and pharmaceuticals. LDHs-nanostructures can be used as drug carriers, especially anti-inflammatory and anti-cancer drugs to treat cancers. Thus, the LDHs should have a number of physicochemical properties to act as a desirable drug carrier. Among the primary factors to increase the efficiency of LDHs are their surface characteristics and size, number and type of ions, rapid clearance from the body after drug release, and non-toxicity. All of these properties make LDHs nano-carriers for carrying anti-inflammatory and anti-cancer drugs to treat a variety of cancers. Therefore, we focus on reviewing the nature of LDH nano-carriers and evaluating the desirable properties for drug delivery, drug loading methods into LDH and anti-inflammatory drug delivery methods, their potential applications in biomedical and their toxicity and antimicrobial effects in breast cancer.https://nmj.mums.ac.ir/article_19917_6380f8c250ff43c1404740cd8a8c10f9.pdfanti-inflammatory drugsbreast cancercancer therapyldh nanostructuresnano-carriers |
| spellingShingle | Kamram Hosseini Saiedeh Razi Soofiyani Reza Eghdam Zamiri Afsaneh Farjami Azita Dilmaghani Mehri Mahdavi Vahideh Tarhriz Vahid Yousefi Layered double hydroxide nanostructures as drug-carriers in treatment of breast cancer Nanomedicine Journal anti-inflammatory drugs breast cancer cancer therapy ldh nanostructures nano-carriers |
| title | Layered double hydroxide nanostructures as drug-carriers in treatment of breast cancer |
| title_full | Layered double hydroxide nanostructures as drug-carriers in treatment of breast cancer |
| title_fullStr | Layered double hydroxide nanostructures as drug-carriers in treatment of breast cancer |
| title_full_unstemmed | Layered double hydroxide nanostructures as drug-carriers in treatment of breast cancer |
| title_short | Layered double hydroxide nanostructures as drug-carriers in treatment of breast cancer |
| title_sort | layered double hydroxide nanostructures as drug carriers in treatment of breast cancer |
| topic | anti-inflammatory drugs breast cancer cancer therapy ldh nanostructures nano-carriers |
| url | https://nmj.mums.ac.ir/article_19917_6380f8c250ff43c1404740cd8a8c10f9.pdf |
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