Rhodococcus equi Joint Sepsis and Osteomyelitis Is Associated With a Grave Prognosis in Foals
The most common pathologic manifestation of Rhodococcus equi, a gram-positive, facultative intracellular bacterium, is pyogranulomatous pneumonia in foals and weanlings. Hematogenous spread of bacteria may subsequently occur, resulting in joint sepsis, osteomyelitis, or subcutaneous abscessation. Me...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-01-01
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| Series: | Frontiers in Veterinary Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fvets.2019.00503/full |
| _version_ | 1818110720118620160 |
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| author | Nicholas A. Ruocco Lauren K. Luedke Lisa A. Fortier Norm G. Ducharme Heidi L. Reesink |
| author_facet | Nicholas A. Ruocco Lauren K. Luedke Lisa A. Fortier Norm G. Ducharme Heidi L. Reesink |
| author_sort | Nicholas A. Ruocco |
| collection | DOAJ |
| description | The most common pathologic manifestation of Rhodococcus equi, a gram-positive, facultative intracellular bacterium, is pyogranulomatous pneumonia in foals and weanlings. Hematogenous spread of bacteria may subsequently occur, resulting in joint sepsis, osteomyelitis, or subcutaneous abscessation. Medical records from horses presenting to the Cornell University Equine Hospital from 1998 to 2018 were reviewed for cases diagnosed with R. equi joint and/or bone infection, and information about case progression and outcome were analyzed. We hypothesized that, despite advances in diagnostic imaging, antimicrobials and antimicrobial delivery methods, the prognosis for R. equi joint sepsis and osteomyelitis remains grave for athletic activity and poor for survival. The 12 cases that met the review criteria had a mortality rate of 84% (10/12), with one case lost to follow up after discharge and one case discharged with a grave prognosis for athleticism. |
| first_indexed | 2024-12-11T02:51:38Z |
| format | Article |
| id | doaj.art-ad8ffa69e8cb4c3e96c6166aa2698d6d |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-11T02:51:38Z |
| publishDate | 2020-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-ad8ffa69e8cb4c3e96c6166aa2698d6d2022-12-22T01:23:18ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692020-01-01610.3389/fvets.2019.00503493781Rhodococcus equi Joint Sepsis and Osteomyelitis Is Associated With a Grave Prognosis in FoalsNicholas A. RuoccoLauren K. LuedkeLisa A. FortierNorm G. DucharmeHeidi L. ReesinkThe most common pathologic manifestation of Rhodococcus equi, a gram-positive, facultative intracellular bacterium, is pyogranulomatous pneumonia in foals and weanlings. Hematogenous spread of bacteria may subsequently occur, resulting in joint sepsis, osteomyelitis, or subcutaneous abscessation. Medical records from horses presenting to the Cornell University Equine Hospital from 1998 to 2018 were reviewed for cases diagnosed with R. equi joint and/or bone infection, and information about case progression and outcome were analyzed. We hypothesized that, despite advances in diagnostic imaging, antimicrobials and antimicrobial delivery methods, the prognosis for R. equi joint sepsis and osteomyelitis remains grave for athletic activity and poor for survival. The 12 cases that met the review criteria had a mortality rate of 84% (10/12), with one case lost to follow up after discharge and one case discharged with a grave prognosis for athleticism.https://www.frontiersin.org/article/10.3389/fvets.2019.00503/fullseptic arthritisseptic physitisorthopedic infectionbone abscessR. equi |
| spellingShingle | Nicholas A. Ruocco Lauren K. Luedke Lisa A. Fortier Norm G. Ducharme Heidi L. Reesink Rhodococcus equi Joint Sepsis and Osteomyelitis Is Associated With a Grave Prognosis in Foals Frontiers in Veterinary Science septic arthritis septic physitis orthopedic infection bone abscess R. equi |
| title | Rhodococcus equi Joint Sepsis and Osteomyelitis Is Associated With a Grave Prognosis in Foals |
| title_full | Rhodococcus equi Joint Sepsis and Osteomyelitis Is Associated With a Grave Prognosis in Foals |
| title_fullStr | Rhodococcus equi Joint Sepsis and Osteomyelitis Is Associated With a Grave Prognosis in Foals |
| title_full_unstemmed | Rhodococcus equi Joint Sepsis and Osteomyelitis Is Associated With a Grave Prognosis in Foals |
| title_short | Rhodococcus equi Joint Sepsis and Osteomyelitis Is Associated With a Grave Prognosis in Foals |
| title_sort | rhodococcus equi joint sepsis and osteomyelitis is associated with a grave prognosis in foals |
| topic | septic arthritis septic physitis orthopedic infection bone abscess R. equi |
| url | https://www.frontiersin.org/article/10.3389/fvets.2019.00503/full |
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