Disruption of FGF Signaling Ameliorates Inflammatory Response in Hepatic Stellate Cells

Disruption of FGF Signaling Ameliorates Inflammatory Response in Hepatic Stellate Cells

It is a well-documented event that fibroblast growth factors (FGFs) regulate liver development and homeostasis in autocrine, paracrine, and endocrine manners via binding and activating FGF receptors (FGFRs) tyrosine kinase in hepatocytes. Recent research reveals that hepatic stellate cells (HSCs) pl...

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Bibliographic Details
Main Authors: Cong Wang, Yuelong Li, Hao Li, Yali Zhang, Zhangguo Ying, Xuye Wang, Tingting Zhang, Wenshu Zhang, Zhichao Fan, Xiaokun Li, Jisheng Ma, Xuebo Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
FGFR
MMP9
hepatic stellate cell
inflammation
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00601/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00601/full

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