N-glycoproteomics of brain synapses and synaptic vesicles

Summary: At mammalian neuronal synapses, synaptic vesicle (SV) glycoproteins are essential for robust neurotransmission. Asparagine (N)-linked glycosylation is required for delivery of the major SV glycoproteins synaptophysin and SV2A to SVs. Despite this key role for N-glycosylation, the molecular...

Description complète

Détails bibliographiques
Auteurs principaux: Mazdak M. Bradberry, Trenton M. Peters-Clarke, Evgenia Shishkova, Edwin R. Chapman, Joshua J. Coon
Format: Article
Langue:English
Publié: Elsevier 2023-04-01
Collection:Cell Reports
Sujets:
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2211124723003790