N-glycoproteomics of brain synapses and synaptic vesicles

Summary: At mammalian neuronal synapses, synaptic vesicle (SV) glycoproteins are essential for robust neurotransmission. Asparagine (N)-linked glycosylation is required for delivery of the major SV glycoproteins synaptophysin and SV2A to SVs. Despite this key role for N-glycosylation, the molecular...

Descrizione completa

Dettagli Bibliografici
Autori principali: Mazdak M. Bradberry, Trenton M. Peters-Clarke, Evgenia Shishkova, Edwin R. Chapman, Joshua J. Coon
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier 2023-04-01
Serie:Cell Reports
Soggetti:
Accesso online:http://www.sciencedirect.com/science/article/pii/S2211124723003790