New Insights into the Pivotal Role of Iron/Heme Metabolism in TLR4/NF-κB Signaling-Mediated Inflammatory Responses in Human Monocytes

New Insights into the Pivotal Role of Iron/Heme Metabolism in TLR4/NF-κB Signaling-Mediated Inflammatory Responses in Human Monocytes

Iron metabolism and heme biosynthesis are essential processes in cells during the energy cycle. Alteration in these processes could create an inflammatory condition, which results in tumorigenesis. Studies are conducted on the exact role of iron/heme metabolism in induced inflammatory conditions. Th...

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Bibliographic Details
Main Authors: Dong Young Kang, Nipin Sp, Eun Seong Jo, Jin-Moo Lee, Kyoung-Jin Jang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
iron metabolism
heme biosynthesis
LPS
high glucose
inflammatory response
TLR4/NF-κB
Online Access:https://www.mdpi.com/2073-4409/10/10/2549

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