The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes
Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-cod...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/5/5030 |
| _version_ | 1797615107539206144 |
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| author | Jiawen Ren Heyue Jin Yumin Zhu |
| author_facet | Jiawen Ren Heyue Jin Yumin Zhu |
| author_sort | Jiawen Ren |
| collection | DOAJ |
| description | Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in the progression of pregnancy, while abnormal expression of placental ncRNAs impacts the onset and development of adverse pregnancy outcomes (APOs). Therefore, we reviewed the current status of research on placental ncRNAs and APOs to further understand the regulatory mechanisms of placental ncRNAs, which provides a new perspective for treating and preventing related diseases. |
| first_indexed | 2024-03-11T07:21:49Z |
| format | Article |
| id | doaj.art-ad98d6e155714f138883b7f27ff520f5 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T07:21:49Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-ad98d6e155714f138883b7f27ff520f52023-11-17T07:56:47ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-03-01245503010.3390/ijms24055030The Role of Placental Non-Coding RNAs in Adverse Pregnancy OutcomesJiawen Ren0Heyue Jin1Yumin Zhu2Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No 81 Meishan Road, Hefei 230032, ChinaDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No 81 Meishan Road, Hefei 230032, ChinaDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No 81 Meishan Road, Hefei 230032, ChinaNon-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in the progression of pregnancy, while abnormal expression of placental ncRNAs impacts the onset and development of adverse pregnancy outcomes (APOs). Therefore, we reviewed the current status of research on placental ncRNAs and APOs to further understand the regulatory mechanisms of placental ncRNAs, which provides a new perspective for treating and preventing related diseases.https://www.mdpi.com/1422-0067/24/5/5030placentamiRNAlncRNAcircRNAadverse pregnancy outcomes |
| spellingShingle | Jiawen Ren Heyue Jin Yumin Zhu The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes International Journal of Molecular Sciences placenta miRNA lncRNA circRNA adverse pregnancy outcomes |
| title | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
| title_full | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
| title_fullStr | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
| title_full_unstemmed | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
| title_short | The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes |
| title_sort | role of placental non coding rnas in adverse pregnancy outcomes |
| topic | placenta miRNA lncRNA circRNA adverse pregnancy outcomes |
| url | https://www.mdpi.com/1422-0067/24/5/5030 |
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