Ginsenoside modified lipid-coated perfluorocarbon nanodroplets: A novel approach to reduce complement protein adsorption and prolong in vivo circulation

Ginsenoside modified lipid-coated perfluorocarbon nanodroplets: A novel approach to reduce complement protein adsorption and prolong in vivo circulation

Lipid-coated perfluorocarbon nanodroplets (lp-NDs) hold great promise in bio-medicine as vehicles for drug delivery, molecular imaging and vaccine agents. However, their clinical utility is restricted by limited targeted accumulation, attributed to the innate immune system (IIS), which acts as the i...

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Bibliographic Details
Main Authors:	Jie Zhou, Binyang Gao, Huan Zhang, Rui Yang, Jianbo Huang, Xin Li, Yi Zhong, Yan Wang, Xiaoxia Zhu, Yan Luo, Feng Yan
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Series:	Acta Pharmaceutica Sinica B
Subjects:	Lipid-coated perfluorocarbon nanodroplets Protein corona Complement C3 Phagocytosis Ginsenoside lipid-coated perfluorocarbon nanodroplets Innate immune system
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211383523004409

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