Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage

Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage

<p>Abstract</p> <p>Mammalian constitutive photomorphogenic 1 (COP1) is a p53 E3 ubiquitin ligase involved in regulating p53 protein level. In plants, the dynamic cytoplasm/nucleus distribution of COP1 is important for its function in terms of catalyzing the degradation of target pr...

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Bibliographic Details
Main Authors: Chen Jian, Velazquez-Torres Guermarie, Zhao Ruiying, Su Chun-Hui, Gully Christopher, Yeung Sai-Ching J, Lee Mong-Hong
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/243

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