SARS-CoV-2 detection in pregnant and non-pregnant women
Background: The coronavirus causing severe acute respiratory syndrome has infected over 2 million people worldwide, killed thousands, and triggered a global pandemic. There is a scarcity of information about pregnant and non-pregnant women who have coronavirus disease (COVID-19). This study’s aim wa...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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IMR Press
2021-10-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805183 |
| _version_ | 1818005931130093568 |
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| author | Noor Hazim Abdulkareem Elham Hazeim Abdulkareem |
| author_facet | Noor Hazim Abdulkareem Elham Hazeim Abdulkareem |
| author_sort | Noor Hazim Abdulkareem |
| collection | DOAJ |
| description | Background: The coronavirus causing severe acute respiratory syndrome has infected over 2 million people worldwide, killed thousands, and triggered a global pandemic. There is a scarcity of information about pregnant and non-pregnant women who have coronavirus disease (COVID-19). This study’s aim was to determine whether the severe acute respiratory syndrome coronavirus 2 was present in the vaginal fluid of infected women. Also, their platelet counts were examined to see whether they were higher in severe versus moderate cases of the COVID-19 disease. Methods: Our Obstetrics Clinic treated 31 women with confirmed COVID-19 (23 pregnant and 8 non-pregnant women) between 1 September 2020 and 30 September 2020). The existence of syndrome coronavirus 2 (SARS-CoV-2) in vaginal fluid samples was used to determine evidence of genital transmission of the virus. A clinical laboratory procedure, including taking blood samples, IgG/IgM Rapid Test Cassette was performed to validate SARS-CoV-2 infection. Vaginal swabs were retrieved from SARS-CoV-2 positive patients between seven and 10 days of onset. Swabs were inserted two or three centimetres into the vagina and rotated three or five times. The swabs were immediately sent to the lab for RT-PCR, and the patients’ COVID-19 status was verified. The real-time Polymerase Chain Reaction (BIORON Diagnostics GmbH’s - RealLine SARS-CoV-2 (B-Format) BI1020-96 Tests). Results: Patients’ vaginal fluids tested negative for SARS-CoV-2. Patients who tested positive for SARS-CoV-2 had normal platelet counts. Discussion: Our findings indicate that SARS-2 virus was not present in the vaginal fluid of the 31 patients, meaning that sexual transmission of SARS-CoV-2 is unlikely. |
| first_indexed | 2024-04-14T04:53:19Z |
| format | Article |
| id | doaj.art-ada67effb7dd42b58a979bb2482fbda9 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-04-14T04:53:19Z |
| publishDate | 2021-10-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-ada67effb7dd42b58a979bb2482fbda92022-12-22T02:11:14ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-10-014851141114510.31083/j.ceog4805183S0390-6663(21)00021-XSARS-CoV-2 detection in pregnant and non-pregnant womenNoor Hazim Abdulkareem0Elham Hazeim Abdulkareem1Department of Obstetrics and Gynecology, University of Anbar, College of Medicine, 55431 Baghdad, Ramadi, IraqDepartment of Oral and Maxillofacial Surgery, University of Anbar, College of Dentistry, 55431 Baghdad, Ramadi, IraqBackground: The coronavirus causing severe acute respiratory syndrome has infected over 2 million people worldwide, killed thousands, and triggered a global pandemic. There is a scarcity of information about pregnant and non-pregnant women who have coronavirus disease (COVID-19). This study’s aim was to determine whether the severe acute respiratory syndrome coronavirus 2 was present in the vaginal fluid of infected women. Also, their platelet counts were examined to see whether they were higher in severe versus moderate cases of the COVID-19 disease. Methods: Our Obstetrics Clinic treated 31 women with confirmed COVID-19 (23 pregnant and 8 non-pregnant women) between 1 September 2020 and 30 September 2020). The existence of syndrome coronavirus 2 (SARS-CoV-2) in vaginal fluid samples was used to determine evidence of genital transmission of the virus. A clinical laboratory procedure, including taking blood samples, IgG/IgM Rapid Test Cassette was performed to validate SARS-CoV-2 infection. Vaginal swabs were retrieved from SARS-CoV-2 positive patients between seven and 10 days of onset. Swabs were inserted two or three centimetres into the vagina and rotated three or five times. The swabs were immediately sent to the lab for RT-PCR, and the patients’ COVID-19 status was verified. The real-time Polymerase Chain Reaction (BIORON Diagnostics GmbH’s - RealLine SARS-CoV-2 (B-Format) BI1020-96 Tests). Results: Patients’ vaginal fluids tested negative for SARS-CoV-2. Patients who tested positive for SARS-CoV-2 had normal platelet counts. Discussion: Our findings indicate that SARS-2 virus was not present in the vaginal fluid of the 31 patients, meaning that sexual transmission of SARS-CoV-2 is unlikely.https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805183covid-19coronavirus infectionpregnancysars-cov-2thrombocytopeniavaginal fluids |
| spellingShingle | Noor Hazim Abdulkareem Elham Hazeim Abdulkareem SARS-CoV-2 detection in pregnant and non-pregnant women Clinical and Experimental Obstetrics & Gynecology covid-19 coronavirus infection pregnancy sars-cov-2 thrombocytopenia vaginal fluids |
| title | SARS-CoV-2 detection in pregnant and non-pregnant women |
| title_full | SARS-CoV-2 detection in pregnant and non-pregnant women |
| title_fullStr | SARS-CoV-2 detection in pregnant and non-pregnant women |
| title_full_unstemmed | SARS-CoV-2 detection in pregnant and non-pregnant women |
| title_short | SARS-CoV-2 detection in pregnant and non-pregnant women |
| title_sort | sars cov 2 detection in pregnant and non pregnant women |
| topic | covid-19 coronavirus infection pregnancy sars-cov-2 thrombocytopenia vaginal fluids |
| url | https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805183 |
| work_keys_str_mv | AT noorhazimabdulkareem sarscov2detectioninpregnantandnonpregnantwomen AT elhamhazeimabdulkareem sarscov2detectioninpregnantandnonpregnantwomen |