Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic background
Alzheimer’s disease (AD) is an age-related and progressive neurodegenerative disease. In this study, we generated an induced pluripotent stem cell (iPSC) line from the dermal fibroblasts of a 69-year-old female patient carrying APOEε3/ε4 allele and diagnosed with sporadic AD. The iPSC line will be a...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506123001289 |
| _version_ | 1797692069649580032 |
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| author | Hui Li Bei Zhang Zhiqiang Shi Hui Wu Shuya Mei Tianyi Ai An Shi Lihui Wang Mingli Zhu Jiajia Tang |
| author_facet | Hui Li Bei Zhang Zhiqiang Shi Hui Wu Shuya Mei Tianyi Ai An Shi Lihui Wang Mingli Zhu Jiajia Tang |
| author_sort | Hui Li |
| collection | DOAJ |
| description | Alzheimer’s disease (AD) is an age-related and progressive neurodegenerative disease. In this study, we generated an induced pluripotent stem cell (iPSC) line from the dermal fibroblasts of a 69-year-old female patient carrying APOEε3/ε4 allele and diagnosed with sporadic AD. The iPSC line will be a useful tool for investigating the pathogenesis mechanisms and for drug tests in AD. |
| first_indexed | 2024-03-12T02:22:24Z |
| format | Article |
| id | doaj.art-ada88a9155af4fafbc6ca9c374e5eec8 |
| institution | Directory Open Access Journal |
| issn | 1873-5061 |
| language | English |
| last_indexed | 2024-03-12T02:22:24Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Stem Cell Research |
| spelling | doaj.art-ada88a9155af4fafbc6ca9c374e5eec82023-09-06T04:50:44ZengElsevierStem Cell Research1873-50612023-09-0171103142Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic backgroundHui Li0Bei Zhang1Zhiqiang Shi2Hui Wu3Shuya Mei4Tianyi Ai5An Shi6Lihui Wang7Mingli Zhu8Jiajia Tang9Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Neurology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, ChinaDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, China; Corresponding authors.Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No.1630 Dongfang Road, Shanghai 200127, China; Corresponding authors.Alzheimer’s disease (AD) is an age-related and progressive neurodegenerative disease. In this study, we generated an induced pluripotent stem cell (iPSC) line from the dermal fibroblasts of a 69-year-old female patient carrying APOEε3/ε4 allele and diagnosed with sporadic AD. The iPSC line will be a useful tool for investigating the pathogenesis mechanisms and for drug tests in AD.http://www.sciencedirect.com/science/article/pii/S1873506123001289 |
| spellingShingle | Hui Li Bei Zhang Zhiqiang Shi Hui Wu Shuya Mei Tianyi Ai An Shi Lihui Wang Mingli Zhu Jiajia Tang Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic background Stem Cell Research |
| title | Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic background |
| title_full | Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic background |
| title_fullStr | Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic background |
| title_full_unstemmed | Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic background |
| title_short | Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic background |
| title_sort | derivation of induced pluripotent stem cell sjtui003 a from a 69 year old chinese han sporadic alzheimer s disease patient with apoeε3 ε4 genetic background |
| url | http://www.sciencedirect.com/science/article/pii/S1873506123001289 |
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