Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease

Sander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2 1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 C...

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Main Authors: Talman S, Uzun S, Djamin RS, Baart SJ, Grootenboers MJJH, Aerts J, van der Eerden M
Format: Article
Language:English
Published: Dove Medical Press 2021-03-01
Series:International Journal of COPD
Subjects:
Online Access:https://www.dovepress.com/long-term-azithromycin-maintenance-treatment-in-patients-with-frequent-peer-reviewed-article-COPD
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author Talman S
Uzun S
Djamin RS
Baart SJ
Grootenboers MJJH
Aerts J
van der Eerden M
author_facet Talman S
Uzun S
Djamin RS
Baart SJ
Grootenboers MJJH
Aerts J
van der Eerden M
author_sort Talman S
collection DOAJ
description Sander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2 1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 CE, the Netherlands; 3Erasmuc Medical Centre Rotterdam, Department of Biostatistics, Rotterdam, 3015 CE, the NetherlandsCorrespondence: Sander Talman Tel +31 76 595 5351Email STalman@amphia.nlAbstract: Macrolides are effective in reducing the number of exacerbations in COPD patients with the frequent exacerbator phenotype. Our study did not show a persistent effect of azithromycin on exacerbation frequencies after more than one year of usage.Keywords: Macrolide, long-term, exacerbations, COPD, COLUMBUS
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spelling doaj.art-adab09f7e71d43ea9dc613ef50b3f6d82022-12-21T19:46:40ZengDove Medical PressInternational Journal of COPD1178-20052021-03-01Volume 1649549862598Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary DiseaseTalman SUzun SDjamin RSBaart SJGrootenboers MJJHAerts Jvan der Eerden MSander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2 1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 CE, the Netherlands; 3Erasmuc Medical Centre Rotterdam, Department of Biostatistics, Rotterdam, 3015 CE, the NetherlandsCorrespondence: Sander Talman Tel +31 76 595 5351Email STalman@amphia.nlAbstract: Macrolides are effective in reducing the number of exacerbations in COPD patients with the frequent exacerbator phenotype. Our study did not show a persistent effect of azithromycin on exacerbation frequencies after more than one year of usage.Keywords: Macrolide, long-term, exacerbations, COPD, COLUMBUShttps://www.dovepress.com/long-term-azithromycin-maintenance-treatment-in-patients-with-frequent-peer-reviewed-article-COPDcopdexacerbationsmacrolidemaintenance-therapy
spellingShingle Talman S
Uzun S
Djamin RS
Baart SJ
Grootenboers MJJH
Aerts J
van der Eerden M
Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease
International Journal of COPD
copd
exacerbations
macrolide
maintenance-therapy
title Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease
title_full Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease
title_fullStr Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease
title_full_unstemmed Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease
title_short Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease
title_sort long term azithromycin maintenance treatment in patients with frequent exacerbations of chronic obstructive pulmonary disease
topic copd
exacerbations
macrolide
maintenance-therapy
url https://www.dovepress.com/long-term-azithromycin-maintenance-treatment-in-patients-with-frequent-peer-reviewed-article-COPD
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