Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease
Sander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2 1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 C...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Dove Medical Press
2021-03-01
|
Series: | International Journal of COPD |
Subjects: | |
Online Access: | https://www.dovepress.com/long-term-azithromycin-maintenance-treatment-in-patients-with-frequent-peer-reviewed-article-COPD |
_version_ | 1818947544136286208 |
---|---|
author | Talman S Uzun S Djamin RS Baart SJ Grootenboers MJJH Aerts J van der Eerden M |
author_facet | Talman S Uzun S Djamin RS Baart SJ Grootenboers MJJH Aerts J van der Eerden M |
author_sort | Talman S |
collection | DOAJ |
description | Sander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2 1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 CE, the Netherlands; 3Erasmuc Medical Centre Rotterdam, Department of Biostatistics, Rotterdam, 3015 CE, the NetherlandsCorrespondence: Sander Talman Tel +31 76 595 5351Email STalman@amphia.nlAbstract: Macrolides are effective in reducing the number of exacerbations in COPD patients with the frequent exacerbator phenotype. Our study did not show a persistent effect of azithromycin on exacerbation frequencies after more than one year of usage.Keywords: Macrolide, long-term, exacerbations, COPD, COLUMBUS |
first_indexed | 2024-12-20T08:32:35Z |
format | Article |
id | doaj.art-adab09f7e71d43ea9dc613ef50b3f6d8 |
institution | Directory Open Access Journal |
issn | 1178-2005 |
language | English |
last_indexed | 2024-12-20T08:32:35Z |
publishDate | 2021-03-01 |
publisher | Dove Medical Press |
record_format | Article |
series | International Journal of COPD |
spelling | doaj.art-adab09f7e71d43ea9dc613ef50b3f6d82022-12-21T19:46:40ZengDove Medical PressInternational Journal of COPD1178-20052021-03-01Volume 1649549862598Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary DiseaseTalman SUzun SDjamin RSBaart SJGrootenboers MJJHAerts Jvan der Eerden MSander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2 1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 CE, the Netherlands; 3Erasmuc Medical Centre Rotterdam, Department of Biostatistics, Rotterdam, 3015 CE, the NetherlandsCorrespondence: Sander Talman Tel +31 76 595 5351Email STalman@amphia.nlAbstract: Macrolides are effective in reducing the number of exacerbations in COPD patients with the frequent exacerbator phenotype. Our study did not show a persistent effect of azithromycin on exacerbation frequencies after more than one year of usage.Keywords: Macrolide, long-term, exacerbations, COPD, COLUMBUShttps://www.dovepress.com/long-term-azithromycin-maintenance-treatment-in-patients-with-frequent-peer-reviewed-article-COPDcopdexacerbationsmacrolidemaintenance-therapy |
spellingShingle | Talman S Uzun S Djamin RS Baart SJ Grootenboers MJJH Aerts J van der Eerden M Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease International Journal of COPD copd exacerbations macrolide maintenance-therapy |
title | Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease |
title_full | Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease |
title_fullStr | Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease |
title_full_unstemmed | Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease |
title_short | Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease |
title_sort | long term azithromycin maintenance treatment in patients with frequent exacerbations of chronic obstructive pulmonary disease |
topic | copd exacerbations macrolide maintenance-therapy |
url | https://www.dovepress.com/long-term-azithromycin-maintenance-treatment-in-patients-with-frequent-peer-reviewed-article-COPD |
work_keys_str_mv | AT talmans longtermazithromycinmaintenancetreatmentinpatientswithfrequentexacerbationsofchronicobstructivepulmonarydisease AT uzuns longtermazithromycinmaintenancetreatmentinpatientswithfrequentexacerbationsofchronicobstructivepulmonarydisease AT djaminrs longtermazithromycinmaintenancetreatmentinpatientswithfrequentexacerbationsofchronicobstructivepulmonarydisease AT baartsj longtermazithromycinmaintenancetreatmentinpatientswithfrequentexacerbationsofchronicobstructivepulmonarydisease AT grootenboersmjjh longtermazithromycinmaintenancetreatmentinpatientswithfrequentexacerbationsofchronicobstructivepulmonarydisease AT aertsj longtermazithromycinmaintenancetreatmentinpatientswithfrequentexacerbationsofchronicobstructivepulmonarydisease AT vandereerdenm longtermazithromycinmaintenancetreatmentinpatientswithfrequentexacerbationsofchronicobstructivepulmonarydisease |