A minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic material

We have presented the case of a symptomatic, primarily infected aortic pseudoaneurysm treated with endovascular stent graft exclusion and adjunctive use of a long-acting biocomposite antibiotic material injected directly into the pseudoaneurysm sac. We have described preparation of the biocomposite...

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Main Authors: Callie E. Dowdy, MD, Matthew J. Dougherty, MD, Matthew F. Carpiniello, MD, Kunal T. Vani, DO, Douglas A. Troutman, DO, Keith D. Calligaro, MD
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468428722001745
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author Callie E. Dowdy, MD
Matthew J. Dougherty, MD
Matthew F. Carpiniello, MD
Kunal T. Vani, DO
Douglas A. Troutman, DO
Keith D. Calligaro, MD
author_facet Callie E. Dowdy, MD
Matthew J. Dougherty, MD
Matthew F. Carpiniello, MD
Kunal T. Vani, DO
Douglas A. Troutman, DO
Keith D. Calligaro, MD
author_sort Callie E. Dowdy, MD
collection DOAJ
description We have presented the case of a symptomatic, primarily infected aortic pseudoaneurysm treated with endovascular stent graft exclusion and adjunctive use of a long-acting biocomposite antibiotic material injected directly into the pseudoaneurysm sac. We have described preparation of the biocomposite antibiotic material and the catheter-directed delivery technique in detail. Although the use of long-acting antibiotic materials such as antibiotic beads has been well described when performing open surgery in an infected field, the application of these materials in endovascular procedures has been less certain. The techniques we have described have the potential to promote field sterilization in a minimally invasive manner for patients with aortic infections who could be poor candidates for open surgery.
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spelling doaj.art-adabef9f1c674fe7a484880fb74582682022-12-28T04:18:55ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872022-12-0184674677A minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic materialCallie E. Dowdy, MD0Matthew J. Dougherty, MD1Matthew F. Carpiniello, MD2Kunal T. Vani, DO3Douglas A. Troutman, DO4Keith D. Calligaro, MD5Correspondence: Callie E. Dowdy, MD, Section of Vascular Surgery, Pennsylvania Hospital, 700 Spruce St, Ste 101, Philadelphia, PA 19106; Section of Vascular Surgery, Pennsylvania Hospital, Philadelphia, PASection of Vascular Surgery, Pennsylvania Hospital, Philadelphia, PASection of Vascular Surgery, Pennsylvania Hospital, Philadelphia, PASection of Vascular Surgery, Pennsylvania Hospital, Philadelphia, PASection of Vascular Surgery, Pennsylvania Hospital, Philadelphia, PASection of Vascular Surgery, Pennsylvania Hospital, Philadelphia, PAWe have presented the case of a symptomatic, primarily infected aortic pseudoaneurysm treated with endovascular stent graft exclusion and adjunctive use of a long-acting biocomposite antibiotic material injected directly into the pseudoaneurysm sac. We have described preparation of the biocomposite antibiotic material and the catheter-directed delivery technique in detail. Although the use of long-acting antibiotic materials such as antibiotic beads has been well described when performing open surgery in an infected field, the application of these materials in endovascular procedures has been less certain. The techniques we have described have the potential to promote field sterilization in a minimally invasive manner for patients with aortic infections who could be poor candidates for open surgery.http://www.sciencedirect.com/science/article/pii/S2468428722001745Infected aortic aneurysmMycotic aneurysmAntibiotic beadsEndovascular infected aneurysm
spellingShingle Callie E. Dowdy, MD
Matthew J. Dougherty, MD
Matthew F. Carpiniello, MD
Kunal T. Vani, DO
Douglas A. Troutman, DO
Keith D. Calligaro, MD
A minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic material
Journal of Vascular Surgery Cases and Innovative Techniques
Infected aortic aneurysm
Mycotic aneurysm
Antibiotic beads
Endovascular infected aneurysm
title A minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic material
title_full A minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic material
title_fullStr A minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic material
title_full_unstemmed A minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic material
title_short A minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic material
title_sort minimally invasive approach to the infected aorta with novel endovascular use of biocomposite antibiotic material
topic Infected aortic aneurysm
Mycotic aneurysm
Antibiotic beads
Endovascular infected aneurysm
url http://www.sciencedirect.com/science/article/pii/S2468428722001745
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