Role of antibody-dependent enhancement (ADE) in the virulence of SARS-CoV-2 and its mitigation strategies for the development of vaccines and immunotherapies to counter COVID-19

Coronavirus disease-2019 (COVID-19) pandemic has become a global threat and death tolls are increasing worldwide. The SARS-CoV-2 though shares similarities with SARS-CoV and MERS-CoV, immunopathology of the novel virus is not understood properly. Previous reports from SARS and MERS-CoV documents tha...

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Bibliographic Details
Main Authors: Kumaragurubaran Karthik, Tuticorin Maragatham Alagesan Senthilkumar, Shanmugasundaram Udhayavel, Gopal Dhinakar Raj
Format: Article
Language:English
Published: Taylor & Francis Group 2020-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2020.1796425