Proteomic Analysis Reveals Grb2 as a Key Regulator of Periodic Mechanical Stress Transduction in Chondrocytes

Proteomic Analysis Reveals Grb2 as a Key Regulator of Periodic Mechanical Stress Transduction in Chondrocytes

Background/Aims: Periodic mechanical stress could significantly promote chondrocyte proliferation and matrix synthesis. However, the mechanisms underlying the ability of chondrocyte detecting and responding to periodic mechanical stimuli have not been well delineated. Methods: Quantitative proteomic...

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Bibliographic Details
Main Authors: Shun Xu, Zeng Li, Zhen Wang, Chenjun Zhai, Wenwei Liang, Chunhui Zhu, Weimin Fan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Proteomic analysis
Chondrocyte
Periodic mechanical stress
Grb2
Online Access:https://www.karger.com/Article/FullText/485646

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