Lamotrigine induced Steven Johnson syndrome: A case report in Al Batool teaching hospital in Diyala governorate
Background: Steven Johnson syndrome (SJS) is a rare disease that is characterized by acute cutaneous manifestation represented by eruptions of the skin and the mucosal membranes. SJS is an immune-mediated disease, a hypersensitive reaction, characterized by hyperpigmentation of the mucous membranes...
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| Format: | Article |
| Language: | English |
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College of medicine/ University of Diyala
2021-06-01
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| Series: | Diyala Journal of Medicine |
| Subjects: | |
| Online Access: | https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/738 |
| _version_ | 1797530886014500864 |
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| author | Sura Qais Mahmood Almaroof Issam Tariq Abdul Wahaab |
| author_facet | Sura Qais Mahmood Almaroof Issam Tariq Abdul Wahaab |
| author_sort | Sura Qais Mahmood Almaroof |
| collection | DOAJ |
| description |
Background: Steven Johnson syndrome (SJS) is a rare disease that is characterized by acute cutaneous manifestation represented by eruptions of the skin and the mucosal membranes. SJS is an immune-mediated disease, a hypersensitive reaction, characterized by hyperpigmentation of the mucous membranes, rash on the skin and multiple bullae and erosions scattered all over the body especially the face, trunk, and the extremities. Many studies reported that the incidence rate of the SJS was about 1.2 – 6 cases/ million each year and it is more common among males while the toxic epidermal necrolysis (TEN) is more common among females. In addition to the cutaneous manifestations.SJS might show multiple systemic manifestations including the liver, lungs and kidneys. In this case we reported the development of Steven Johnson syndrome in relation to the use of lamotrigine antiepileptic drug.
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| first_indexed | 2024-03-10T10:35:26Z |
| format | Article |
| id | doaj.art-adb084fc8bf3404dae601e4cd4b46f30 |
| institution | Directory Open Access Journal |
| issn | 2219-9764 2617-8982 |
| language | English |
| last_indexed | 2024-03-10T10:35:26Z |
| publishDate | 2021-06-01 |
| publisher | College of medicine/ University of Diyala |
| record_format | Article |
| series | Diyala Journal of Medicine |
| spelling | doaj.art-adb084fc8bf3404dae601e4cd4b46f302023-11-21T23:20:40ZengCollege of medicine/ University of DiyalaDiyala Journal of Medicine2219-97642617-89822021-06-01202Lamotrigine induced Steven Johnson syndrome: A case report in Al Batool teaching hospital in Diyala governorateSura Qais Mahmood Almaroof Issam Tariq Abdul Wahaab Background: Steven Johnson syndrome (SJS) is a rare disease that is characterized by acute cutaneous manifestation represented by eruptions of the skin and the mucosal membranes. SJS is an immune-mediated disease, a hypersensitive reaction, characterized by hyperpigmentation of the mucous membranes, rash on the skin and multiple bullae and erosions scattered all over the body especially the face, trunk, and the extremities. Many studies reported that the incidence rate of the SJS was about 1.2 – 6 cases/ million each year and it is more common among males while the toxic epidermal necrolysis (TEN) is more common among females. In addition to the cutaneous manifestations.SJS might show multiple systemic manifestations including the liver, lungs and kidneys. In this case we reported the development of Steven Johnson syndrome in relation to the use of lamotrigine antiepileptic drug. https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/738Lamotrigine; epidermal detachment; toxic epidermal necrosis ; Stevens johnson syndrome |
| spellingShingle | Sura Qais Mahmood Almaroof Issam Tariq Abdul Wahaab Lamotrigine induced Steven Johnson syndrome: A case report in Al Batool teaching hospital in Diyala governorate Diyala Journal of Medicine Lamotrigine; epidermal detachment; toxic epidermal necrosis ; Stevens johnson syndrome |
| title | Lamotrigine induced Steven Johnson syndrome: A case report in Al Batool teaching hospital in Diyala governorate |
| title_full | Lamotrigine induced Steven Johnson syndrome: A case report in Al Batool teaching hospital in Diyala governorate |
| title_fullStr | Lamotrigine induced Steven Johnson syndrome: A case report in Al Batool teaching hospital in Diyala governorate |
| title_full_unstemmed | Lamotrigine induced Steven Johnson syndrome: A case report in Al Batool teaching hospital in Diyala governorate |
| title_short | Lamotrigine induced Steven Johnson syndrome: A case report in Al Batool teaching hospital in Diyala governorate |
| title_sort | lamotrigine induced steven johnson syndrome a case report in al batool teaching hospital in diyala governorate |
| topic | Lamotrigine; epidermal detachment; toxic epidermal necrosis ; Stevens johnson syndrome |
| url | https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/738 |
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