Reduced Mid1 expression and delayed neuromotor development in daDREAM transgenic mice

Reduced Mid1 expression and delayed neuromotor development in daDREAM transgenic mice

DREAM (downstream regulatory element antagonist modulator) is a Ca2+-binding protein that binds DNA and represses transcription in a Ca2+-dependent manner. Previous work has shown a role for DREAM in cerebellar function regulating the expression of the sodium/calcium exchanger 3 (NCX3) in cerebellar...

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Main Authors: Mara eDierssen, Laura eFedrizzi, Rosa eGomez-Villafuertes, Maria eMartinez de Lagran, Alfonso eGutierrez-Adan, Ignaci eSahun, Belen ePintado, Juan Carlos Oliveros, Xose Manuel Dopazo, Paz eGonzalez, Marisa eBrini, Britt eMellstrom, Ernesto eCarafoli, JOSE R. NARANJO
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Cerebellum
Transgenic mice
Ca2+-dependent gene expression
daDREAM
Genome-wide analysis
Midline 1 gene
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00058/full

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http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00058/full

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