Predicting Antibody Developability Profiles Through Early Stage Discovery Screening

Predicting Antibody Developability Profiles Through Early Stage Discovery Screening

Monoclonal antibodies play an increasingly important role for the development of new drugs across multiple therapy areas. The term ‘developability’ encompasses the feasibility of molecules to successfully progress from discovery to development via evaluation of their physicochemical properties. Thes...

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Bibliographic Details
Main Authors: Marc Bailly, Carl Mieczkowski, Veronica Juan, Essam Metwally, Daniela Tomazela, Jeanne Baker, Makiko Uchida, Ester Kofman, Fahimeh Raoufi, Soha Motlagh, Yao Yu, Jihea Park, Smita Raghava, John Welsh, Michael Rauscher, Gopalan Raghunathan, Mark Hsieh, Yi-Ling Chen, Hang Thu Nguyen, Nhung Nguyen, Dan Cipriano, Laurence Fayadat-Dilman
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:mAbs
Subjects:
Monoclonal antibodies
developability
protein analytics
biophysical properties
protein engineering
antibody discovery
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2020.1743053

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