Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, India

Background and Objective: To determine the prevalence of chronic kidney disease (CKD) and incidence of acute kidney injury (AKI) in patients with coronary artery disease (CAD) demonstrated on coronary angiography. Materials and Methods: Totally, 125 patients admitted to Lilavati Hospital and Resear...

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Main Authors: Pavan Malleshappa, Bharat V Shah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Heart Views
Subjects:
Online Access:http://www.heartviews.org/article.asp?issn=1995-705X;year=2015;volume=16;issue=2;spage=47;epage=52;aulast=Malleshappa
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author Pavan Malleshappa
Bharat V Shah
author_facet Pavan Malleshappa
Bharat V Shah
author_sort Pavan Malleshappa
collection DOAJ
description Background and Objective: To determine the prevalence of chronic kidney disease (CKD) and incidence of acute kidney injury (AKI) in patients with coronary artery disease (CAD) demonstrated on coronary angiography. Materials and Methods: Totally, 125 patients admitted to Lilavati Hospital and Research Centre, Mumbai, with CAD were included in the study. Results: Left anterior descending artery was the major vessel involved (40%), followed by a circumflex artery (21.6%). 49 out of 125 (39.2%) were found to have underlying CKD. 69% (34) of these CKD patients developed AKI. 21 out of 34 patients who developed AKI required hemodialysis. Only 47.1% (16 out of 34) of CKD patients had complete recovery, 29% had partial recovery, and 23% had no recovery of their renal function from AKI. Statistically significant number of patients in CKD group had no recovery from AKI as compared to non-CKD group (23.5% vs. 0%). Conclusion: Our study concludes that there is a very high prevalence of CKD (39.2%) in patients with CAD and AKI is a very important complication (38.4%) in these patients. Considering such a high prevalence of CKD, nephrology referral must be considered in patients with abnormal urinalysis, spot urinary protein to creatinine ratio and in patients whose creatinine clearance is <60 ml/min.
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spelling doaj.art-adb2296fa3ea4742a313f05180f96cd12022-12-21T17:56:25ZengWolters Kluwer Medknow PublicationsHeart Views1995-705X2015-01-01162475210.4103/1995-705X.159219Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, IndiaPavan MalleshappaBharat V ShahBackground and Objective: To determine the prevalence of chronic kidney disease (CKD) and incidence of acute kidney injury (AKI) in patients with coronary artery disease (CAD) demonstrated on coronary angiography. Materials and Methods: Totally, 125 patients admitted to Lilavati Hospital and Research Centre, Mumbai, with CAD were included in the study. Results: Left anterior descending artery was the major vessel involved (40%), followed by a circumflex artery (21.6%). 49 out of 125 (39.2%) were found to have underlying CKD. 69% (34) of these CKD patients developed AKI. 21 out of 34 patients who developed AKI required hemodialysis. Only 47.1% (16 out of 34) of CKD patients had complete recovery, 29% had partial recovery, and 23% had no recovery of their renal function from AKI. Statistically significant number of patients in CKD group had no recovery from AKI as compared to non-CKD group (23.5% vs. 0%). Conclusion: Our study concludes that there is a very high prevalence of CKD (39.2%) in patients with CAD and AKI is a very important complication (38.4%) in these patients. Considering such a high prevalence of CKD, nephrology referral must be considered in patients with abnormal urinalysis, spot urinary protein to creatinine ratio and in patients whose creatinine clearance is <60 ml/min.http://www.heartviews.org/article.asp?issn=1995-705X;year=2015;volume=16;issue=2;spage=47;epage=52;aulast=MalleshappaAcute kidney injurychronic kidney diseasecoronary artery diseasehemodialysis
spellingShingle Pavan Malleshappa
Bharat V Shah
Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, India
Heart Views
Acute kidney injury
chronic kidney disease
coronary artery disease
hemodialysis
title Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, India
title_full Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, India
title_fullStr Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, India
title_full_unstemmed Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, India
title_short Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, India
title_sort prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in mumbai india
topic Acute kidney injury
chronic kidney disease
coronary artery disease
hemodialysis
url http://www.heartviews.org/article.asp?issn=1995-705X;year=2015;volume=16;issue=2;spage=47;epage=52;aulast=Malleshappa
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