Development and Evaluation of Vero Cell-Derived Master Donor Viruses for Influenza Pandemic Preparedness
The embryonated egg-based platform currently produces the majority of seasonal influenza vaccines by employing a well-developed master donor virus (MDV, A/PR/8/34 (PR8)) to generate high-growth reassortants (HGRs) for A/H1N1 and A/H3N2 subtypes. Although the egg-based platform can supply enough seas...
Main Authors: | Po-Ling Chen, Tsai-Teng Tzeng, Alan Yung-Chih Hu, Lily Hui-Ching Wang, Min-Shi Lee |
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Format: | Article |
Jezik: | English |
Izdano: |
MDPI AG
2020-10-01
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Serija: | Vaccines |
Teme: | |
Online dostop: | https://www.mdpi.com/2076-393X/8/4/626 |
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