The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients

Studies have shown that fibrinolysis activity is insufficient in COVID-19 patients. Plasminogen activator inhibitor-1 (PAI-1) is an important antifibrinolytic molecule that plays a key role in the fibrinolytic system. In our study; we aimed to evaluate serum PAI-1 and other biochemical parameters of...

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Main Authors: Baltan Ecem, Serin Erdinç, Avci Burak Yasin, Akilli Işil Kibar, Çinar Ayşe Sürhan
Format: Article
Language:English
Published: De Gruyter 2022-10-01
Series:Türk Biyokimya Dergisi
Subjects:
Online Access:https://doi.org/10.1515/tjb-2022-0044
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author Baltan Ecem
Serin Erdinç
Avci Burak Yasin
Akilli Işil Kibar
Çinar Ayşe Sürhan
author_facet Baltan Ecem
Serin Erdinç
Avci Burak Yasin
Akilli Işil Kibar
Çinar Ayşe Sürhan
author_sort Baltan Ecem
collection DOAJ
description Studies have shown that fibrinolysis activity is insufficient in COVID-19 patients. Plasminogen activator inhibitor-1 (PAI-1) is an important antifibrinolytic molecule that plays a key role in the fibrinolytic system. In our study; we aimed to evaluate serum PAI-1 and other biochemical parameters of COVID-19 patients in terms of disease course and mortality.
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spelling doaj.art-adb574aa1d124da3b7e446bc30eee3a22022-12-22T03:45:31ZengDe GruyterTürk Biyokimya Dergisi1303-829X2022-10-0147567267910.1515/tjb-2022-0044The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patientsBaltan Ecem0Serin Erdinç1Avci Burak Yasin2Akilli Işil Kibar3Çinar Ayşe Sürhan4Medical Biochemistry, Istanbul Şişli Hamidiye Etfal Training and Research Hospital, Sisli, TurkeyMedical Biochemistry, Istanbul Şişli Hamidiye Etfal Training and Research Hospital, Sisli, TurkeyAmasya University, Amasya, TurkeyDepartment of Chest Diseases, Istanbul Şişli Hamidiye Etfal Training and Research Hospital, Sisli, TurkeyDeparment of Anesthesiology and Reanimation, Istanbul Şişli Hamidiye Etfal Training and Research Hospital, Sisli, TurkeyStudies have shown that fibrinolysis activity is insufficient in COVID-19 patients. Plasminogen activator inhibitor-1 (PAI-1) is an important antifibrinolytic molecule that plays a key role in the fibrinolytic system. In our study; we aimed to evaluate serum PAI-1 and other biochemical parameters of COVID-19 patients in terms of disease course and mortality.https://doi.org/10.1515/tjb-2022-0044biochemicalcovid-19fibrinolysismortalitypai-1
spellingShingle Baltan Ecem
Serin Erdinç
Avci Burak Yasin
Akilli Işil Kibar
Çinar Ayşe Sürhan
The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients
Türk Biyokimya Dergisi
biochemical
covid-19
fibrinolysis
mortality
pai-1
title The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients
title_full The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients
title_fullStr The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients
title_full_unstemmed The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients
title_short The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients
title_sort relationship between plasminogen activator inhibitor 1 levels and the course of disease in covid 19 patients
topic biochemical
covid-19
fibrinolysis
mortality
pai-1
url https://doi.org/10.1515/tjb-2022-0044
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