The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients
Studies have shown that fibrinolysis activity is insufficient in COVID-19 patients. Plasminogen activator inhibitor-1 (PAI-1) is an important antifibrinolytic molecule that plays a key role in the fibrinolytic system. In our study; we aimed to evaluate serum PAI-1 and other biochemical parameters of...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
De Gruyter
2022-10-01
|
Series: | Türk Biyokimya Dergisi |
Subjects: | |
Online Access: | https://doi.org/10.1515/tjb-2022-0044 |
_version_ | 1811213303502864384 |
---|---|
author | Baltan Ecem Serin Erdinç Avci Burak Yasin Akilli Işil Kibar Çinar Ayşe Sürhan |
author_facet | Baltan Ecem Serin Erdinç Avci Burak Yasin Akilli Işil Kibar Çinar Ayşe Sürhan |
author_sort | Baltan Ecem |
collection | DOAJ |
description | Studies have shown that fibrinolysis activity is insufficient in COVID-19 patients. Plasminogen activator inhibitor-1 (PAI-1) is an important antifibrinolytic molecule that plays a key role in the fibrinolytic system. In our study; we aimed to evaluate serum PAI-1 and other biochemical parameters of COVID-19 patients in terms of disease course and mortality. |
first_indexed | 2024-04-12T05:44:24Z |
format | Article |
id | doaj.art-adb574aa1d124da3b7e446bc30eee3a2 |
institution | Directory Open Access Journal |
issn | 1303-829X |
language | English |
last_indexed | 2024-04-12T05:44:24Z |
publishDate | 2022-10-01 |
publisher | De Gruyter |
record_format | Article |
series | Türk Biyokimya Dergisi |
spelling | doaj.art-adb574aa1d124da3b7e446bc30eee3a22022-12-22T03:45:31ZengDe GruyterTürk Biyokimya Dergisi1303-829X2022-10-0147567267910.1515/tjb-2022-0044The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patientsBaltan Ecem0Serin Erdinç1Avci Burak Yasin2Akilli Işil Kibar3Çinar Ayşe Sürhan4Medical Biochemistry, Istanbul Şişli Hamidiye Etfal Training and Research Hospital, Sisli, TurkeyMedical Biochemistry, Istanbul Şişli Hamidiye Etfal Training and Research Hospital, Sisli, TurkeyAmasya University, Amasya, TurkeyDepartment of Chest Diseases, Istanbul Şişli Hamidiye Etfal Training and Research Hospital, Sisli, TurkeyDeparment of Anesthesiology and Reanimation, Istanbul Şişli Hamidiye Etfal Training and Research Hospital, Sisli, TurkeyStudies have shown that fibrinolysis activity is insufficient in COVID-19 patients. Plasminogen activator inhibitor-1 (PAI-1) is an important antifibrinolytic molecule that plays a key role in the fibrinolytic system. In our study; we aimed to evaluate serum PAI-1 and other biochemical parameters of COVID-19 patients in terms of disease course and mortality.https://doi.org/10.1515/tjb-2022-0044biochemicalcovid-19fibrinolysismortalitypai-1 |
spellingShingle | Baltan Ecem Serin Erdinç Avci Burak Yasin Akilli Işil Kibar Çinar Ayşe Sürhan The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients Türk Biyokimya Dergisi biochemical covid-19 fibrinolysis mortality pai-1 |
title | The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients |
title_full | The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients |
title_fullStr | The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients |
title_full_unstemmed | The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients |
title_short | The relationship between plasminogen activator inhibitor-1 levels and the course of disease in COVID-19 patients |
title_sort | relationship between plasminogen activator inhibitor 1 levels and the course of disease in covid 19 patients |
topic | biochemical covid-19 fibrinolysis mortality pai-1 |
url | https://doi.org/10.1515/tjb-2022-0044 |
work_keys_str_mv | AT baltanecem therelationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT serinerdinc therelationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT avciburakyasin therelationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT akilliisilkibar therelationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT cinaraysesurhan therelationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT baltanecem relationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT serinerdinc relationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT avciburakyasin relationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT akilliisilkibar relationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients AT cinaraysesurhan relationshipbetweenplasminogenactivatorinhibitor1levelsandthecourseofdiseaseincovid19patients |