Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes

Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes

The potential of marine benthic cyanobacteria as a source of anticancer drug candidates was assessed in a screen for induction of cell death (apoptosis) in acute myeloid leukemia (AML) cells. Of the 41 marine cyanobacterial strains screened, more than half contained cell death-inducing activity. Sev...

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Bibliographic Details
Main Authors: Stein Ove Døskeland, Lars Herfindal, Kaarina Sivonen, Matti Wahlsten, Frode Selheim, Linn Oftedal
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Marine Drugs
Subjects:
AML
cyanobacteria
apoptosis
cancer
leukemia
Online Access:http://www.mdpi.com/1660-3397/8/10/2659/

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