Origin and Evolution of RNA-Dependent RNA Polymerase
RNA-dependent RNA polymerases (RdRp) are very ancient enzymes and are essential for all viruses with RNA genomes. We reconstruct the origin and evolution of this polymerase since the initial stages of the origin of life. The origin of the RdRp was traced back from tRNA ancestors. At the origin of th...
Main Authors: | Savio T. de Farias, Ariosvaldo P. dos Santos Junior, Thais G. Rêgo, Marco V. José |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-09-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fgene.2017.00125/full |
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