Longer Lag Time in Early-Stage Retinoblastoma
Highlights: • Patients with IRSS I stage have the longest lag time than IVB stage. • Lag time is no significant with stage retinoblastoma. Abstract: Retinoblastoma is a rare neoplasm disease that occurs in children, generally under the age of two. Retinoblastoma is more prevalent in develo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universitas Airlangga
2022-06-01
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| Series: | Folia Medica Indonesiana |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/FMI/article/view/24975 |
| _version_ | 1811241343594266624 |
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| author | Anindya Citra Budi Utomo Hendrian Dwikoloso Soebagjo |
| author_facet | Anindya Citra Budi Utomo Hendrian Dwikoloso Soebagjo |
| author_sort | Anindya Citra |
| collection | DOAJ |
| description | Highlights:
• Patients with IRSS I stage have the longest lag time than IVB stage.
• Lag time is no significant with stage retinoblastoma.
Abstract:
Retinoblastoma is a rare neoplasm disease that occurs in children, generally under the age of two. Retinoblastoma is more prevalent in developing countries and is often associated with a late diagnosis. Such delays can lead to a poor prognosis. The time from the appearance of symptoms of retinoblastoma (onset) to the time of diagnosis is called lag time. Early diagnosis of retinoblastoma by paying attention to factors such as age, clinical symptoms, and laterality can help improve retinoblastoma survival rates, especially in developing countries. The purpose of this study was to analyze the relationship between the lag time to the stage of retinoblastoma patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. This study was a retrospective analytical observational study using secondary data from retinoblastoma patients at the Ophthalmology Outpatient Unit at Dr. Soetomo General Academic Hospital, Surabaya, from January 2014 to December 2018. The data were analyzed using Kendall's tau-C test. No significant correlation was found between lag time and stage (p = 0.339). Patients with International Retinoblastoma Staging System (IRSS) I stage had the longest lag time (on average 28 months), and patients with stage IVB had the shortest lag time (on average four months). There was no correlation between lag time and retinoblastoma stage. However, there was a trend of patients with early stages delaying hospital visits, while patients with advanced stages in earlier to the hospital. |
| first_indexed | 2024-04-12T13:34:57Z |
| format | Article |
| id | doaj.art-adb8fa06e6714eeaad3ccb067786cfc1 |
| institution | Directory Open Access Journal |
| issn | 2355-8393 2599-056X |
| language | English |
| last_indexed | 2024-04-12T13:34:57Z |
| publishDate | 2022-06-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Folia Medica Indonesiana |
| spelling | doaj.art-adb8fa06e6714eeaad3ccb067786cfc12022-12-22T03:31:04ZengUniversitas AirlanggaFolia Medica Indonesiana2355-83932599-056X2022-06-0158210310710.20473/fmi.v58i2.2497520458Longer Lag Time in Early-Stage RetinoblastomaAnindya Citra0Budi Utomo1https://orcid.org/0000-0002-1147-3263Hendrian Dwikoloso Soebagjo2https://orcid.org/0000-0002-0768-1545Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, IndonesiaDepartment of Public Health and Preventive Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, IndonesiaDepartment of Ophthalmology, Faculty of Medicine, Universitas Airlangga, Surabaya, IndonesiaHighlights: • Patients with IRSS I stage have the longest lag time than IVB stage. • Lag time is no significant with stage retinoblastoma. Abstract: Retinoblastoma is a rare neoplasm disease that occurs in children, generally under the age of two. Retinoblastoma is more prevalent in developing countries and is often associated with a late diagnosis. Such delays can lead to a poor prognosis. The time from the appearance of symptoms of retinoblastoma (onset) to the time of diagnosis is called lag time. Early diagnosis of retinoblastoma by paying attention to factors such as age, clinical symptoms, and laterality can help improve retinoblastoma survival rates, especially in developing countries. The purpose of this study was to analyze the relationship between the lag time to the stage of retinoblastoma patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. This study was a retrospective analytical observational study using secondary data from retinoblastoma patients at the Ophthalmology Outpatient Unit at Dr. Soetomo General Academic Hospital, Surabaya, from January 2014 to December 2018. The data were analyzed using Kendall's tau-C test. No significant correlation was found between lag time and stage (p = 0.339). Patients with International Retinoblastoma Staging System (IRSS) I stage had the longest lag time (on average 28 months), and patients with stage IVB had the shortest lag time (on average four months). There was no correlation between lag time and retinoblastoma stage. However, there was a trend of patients with early stages delaying hospital visits, while patients with advanced stages in earlier to the hospital.https://e-journal.unair.ac.id/FMI/article/view/24975retinoblastomalag timeirss stagediseaseneglected disease |
| spellingShingle | Anindya Citra Budi Utomo Hendrian Dwikoloso Soebagjo Longer Lag Time in Early-Stage Retinoblastoma Folia Medica Indonesiana retinoblastoma lag time irss stage disease neglected disease |
| title | Longer Lag Time in Early-Stage Retinoblastoma |
| title_full | Longer Lag Time in Early-Stage Retinoblastoma |
| title_fullStr | Longer Lag Time in Early-Stage Retinoblastoma |
| title_full_unstemmed | Longer Lag Time in Early-Stage Retinoblastoma |
| title_short | Longer Lag Time in Early-Stage Retinoblastoma |
| title_sort | longer lag time in early stage retinoblastoma |
| topic | retinoblastoma lag time irss stage disease neglected disease |
| url | https://e-journal.unair.ac.id/FMI/article/view/24975 |
| work_keys_str_mv | AT anindyacitra longerlagtimeinearlystageretinoblastoma AT budiutomo longerlagtimeinearlystageretinoblastoma AT hendriandwikolososoebagjo longerlagtimeinearlystageretinoblastoma |